ArticleClinical and experimental immunology1977
Ultrastructural observations on the in vitro interaction between rat eosinophils and some parasitic helminths (Schistosoma mansoni, Trichinella spiralis and Nippostrongylus brasiliensis).
Article in Clinical and experimental immunology, 1977. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
35 citing papers in PubMed, 139 citations in OpenAlex.
- Eosinophil biology in COPD: from scientific insight to clinical treatment action.ERJ open research · 2026Review
- A Natural Enzyme GOx-MOF Cascade Complex Killing Zoonotic Parasite Trichinella spiralis by Energy Utilization Limitation and Generated Free Radicals.Transboundary and emerging diseases · 2026Article
- Intestinal helminth infection promotes IL-5- and CD4Mucosal immunology · 2019Article
- Contemporary understanding of the secretory granules in human eosinophils.Journal of leukocyte biology · 2018Review
- CD63 is tightly associated with intracellular, secretory events chaperoning piecemeal degranulation and compound exocytosis in human eosinophils.Journal of leukocyte biology · 2016Article
- Eosinophil-derived cytokines in health and disease: unraveling novel mechanisms of selective secretion.Allergy · 2013Review
- Article
- Preparation of secretory vesicle-free plasma membranes by isopycnic sucrose gradient fractionation of neutrophils purified by the gelatin method.Cytotechnology · 2004Article
- Cysteine protease secreted by Paragonimus westermani attenuates effector functions of human eosinophils stimulated with immunoglobulin G.Infection and immunity · 2001Article
- Differential regulation of granule-to-granule and granule-to-plasma membrane fusion during secretion from rat pituitary lactotrophs.The Journal of cell biology · 2000Article
- Cell-adhesion molecules expressed by activated eosinophils in Onchocerca volvulus infection.Parasitology research · 1995Article
- Focal exocytosis by eosinophils--compound exocytosis and cumulative fusion.The EMBO journal · 1993Article
- Article
- Eosinophils as effector cells in immunity and hypersensitivity disorders.Clinical and experimental immunology · 1985Review
- Ultrastructure of the attack of eosinophils stimulated by blood mononuclear cell products on schistosomula of Schistosoma mansoni.The American journal of pathology · 1985Article
- Further characterization of human eosinophil peroxidase.The Biochemical journal · 1985Article
- Electron-microscopic and immunohistochemical studies on endomyocardial biopsies from a patient with eosinophilic endomyocardial disease.Heart and vessels. Supplement · 1985Article
- Toxic effect of the peroxidase-hydrogen peroxide-halide antimicrobial system on Mycobacterium leprae.Infection and immunity · 1984Article
- Myeloperoxidase is more efficient than eosinophil peroxidase in the in vitro killing of newborn larvae of Trichinella spiralis.Immunology · 1984Article
- Horse eosinophil degranulation induced by the ionophore A23187. Ultrastructure and role of phospholipase A2.The American journal of pathology · 1983Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rat eosinophils form an intimate association with the surfaces of parasitic helminths, in vitro, in the presence of immune serum. The parasite presents a non-phagocytosable surface to the cell. The initial response of the eosinophil is degranulation which leads to the formation of large cytoplasmic vacuoles. Peroxidase, an enzyme localized in the matrix of the crystalloid secretion granules, is discharged into these vacuoles as a consequence of degranulation. The vacuoles eventually become connected to the adherent basal plasma membrane of the eosinophil, and peroxidase is secreted directly onto the surface of the parasite. There is no morphological evidence to suggest that this particular secretion affects the integrity of the parasite surface.
Indexed as
Identifiers
564249PMC1541177W2247067722What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.