ArticleThe New England journal of medicine1979
Should operations be regionalized? The empirical relation between surgical volume and mortality.
Article in The New England journal of medicine, 1979. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 420 papers, 18 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
420 citing papers in PubMed, 18 syntheses or guidelines pooled it.
- The Impact of Hospital Volume on Postoperative Outcomes for Esophagectomy and Gastrectomy: A Systematic Review and Meta-analysis.Annals of surgical oncology · 2026Pooled it
- An updated systematic review of the impact of volume of surgery and specialization in Norwood procedure.BMC pediatrics · 2026Pooled it
- Development of a core outcome set for studies on centralization of healthcare services.BMC health services research · 2026Pooled it
- Impact of Centralizing Esophageal Cancer Surgery at High-Volume Centers on Long-Term Survival: Individual Patient Data Meta-Analysis.Annals of surgical oncology · 2025Pooled it
- Volume-outcome relationship in corrective surgery for Hirschsprung's disease: a systematic literature review of direct evidence and an overview of indirect evidence.Pediatric surgery international · 2025Pooled it
- Pooled it
- Contemporary analysis of the learning curve for robotic-assisted total hip arthroplasty emerging technologies.Journal of robotic surgery · 2024Pooled it
- European Society of Coloproctology guideline on training in robotic colorectal surgery (2024).Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024Guideline
- Navigating the learning curve: assessing caseload and comparing outcomes before and after the learning curve of computer-navigated total hip arthroplasty.Journal of robotic surgery · 2024Pooled it
- Systematic Review and Meta-analysis of the Association Between Radiation Therapy Treatment Volume and Patient Outcomes.International journal of radiation oncology, biology, physics · 2023Pooled it
- Volume-outcome relationship in intra-abdominal robotic-assisted surgery: a systematic review.Journal of robotic surgery · 2023Pooled it
- Mortality factors in pancreatic surgery: A systematic review. How important is the hospital volume?International journal of surgery (London, England) · 2022Pooled it
- Relationship between annualized case volume and in-hospital motality in subarachnoid hemorrhage: A systematic review and meta-analysis.Medicine · 2021Pooled it
- The learning curve for the direct anterior total hip arthroplasty: a systematic review.International orthopaedics · 2021Pooled it
- Certificate of need laws: a systematic review and cost-effectiveness analysis.BMC health services research · 2020Pooled it
- Pooled it
- Enhancing ovarian cancer care: a systematic review of guideline adherence and clinical variation.BMC public health · 2019Pooled it
- Relationship between surgeon volume and outcomes: a systematic review of systematic reviews.Systematic reviews · 2016Pooled it
- [Management of complications of the upper gastrointestinal tract following external primary procedures : Case series on complex clinical courses and continuation of treatment at a high-volume center].Chirurgie (Heidelberg, Germany) · 2026Article
- Speaking Volumes About High-Volume Centers.Annals of surgical oncology · 2026Article
360 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study examines mortality rates for 12 surgical procedures of varying complexity in 1498 hospitals to determine whether there is a relation between a hospital's surgical volume and its surgical mortality. The mortality of open-heart surgery, vascular surgery, transurethral resection of the prostate, and coronary bypass decreased with increasing number of operations. Hospitals in which 200 or more of these operations were done annually had death rates, adjusted for case mix, 25 to 41 per cent lower than hospitals with lower volumes. For other procedures, the mortality curve flattened at lower volumes. For example, hospitals doing 50 to 100 total hip replacements attained a mortality rate for this procedure almost as low as that of hospitals doing 200 or more. Some procedures, such as cholecystectomy, showed no relation between volume and mortality. The results may reflect the effect of volume or experience on mortality, or referrals to institutions with better outcomes, as well as a number of other factors, such as patient selection. Regardless of the explanation, these data support the value of regionalization for certain operations.
Indexed as
Identifiers
503167What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.