Evidence map›Paper›PMID 4835750›Full record

ArticleThe American journal of cardiology1974

Role of diabetes in congestive heart failure: the Framingham study.

W B Kannel, M Hjortland, W P Castelli

6 registry-linked trialsAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in The American journal of cardiology, 1974. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 743 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
743citing papers in PubMed, 6 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00577590 nacompletedstarted 2003, after this paper: background citation

Cyclotron Produced Isotopes in Biology and Medicine, Project 3: Specific Aim 1A and 1B Effects of Fatty Acid Delivery on Myocardial Metabolism and Function in Type 2 Diabetes (T2DM)

Ran2003Enrolled78Registered outcomes1Posted comparisons0ConditionsDiabetes Mellitus, Type IIArmsLovaza, Metformin, Rosiglitazone
Open the trial in the graph
NCT02655770 phase4completedstarted 2016, after this paper: background citation

Influence of Liraglutide on Diastolic Cardiac Function and Myocardial Perfusion as Determined by Magnetic Resonance Imaging in Patients With Type 2 Diabetes: a Double-blind Randomized Parallel-group Trial

Ran2016Enrolled40Registered outcomes4Posted comparisons0ConditionsCardiac MRI, Diabetes Mellitus Type 2, Diastolic Dysfunction, Myocardial PerfusionArmsliraglutide, Placebo
Open the trial in the graph
NCT00469911 nacompletednot on this mapstarted 2005, after this paper: background citation

Quantification of Intramyocardial Lipid by Proton Magnetic Resonance Spectroscopy

TypeinterventionalSponsorWashington University School of MedicineRan2005 to 2009Enrolled18ConditionsHeart TransplantationArmsMagnetic Resonance Spectroscopy, Ex vivo heart biopsy
NCT01752842 nacompletednot on this mapstarted 2013, after this paper: background citation

Lipid Biomarkers for Diabetic Heart Disease

TypeinterventionalSponsorWashington University School of MedicineRan2013 to 2018Enrolled70ConditionsType II Diabetes Mellitus, Diabetes ComplicationsArmsFenofibrate, Placebo for fenofibrate
NCT03794518 phase3unknown statusnot on this mapstarted 2019, after this paper: background citation

Effect of Combination Therapy With Dapagliflozin Plus Low Dose Pioglitazone on Hospitalization Rate in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction

TypeinterventionalSponsorHamad Medical CorporationRan2019 to 2021Enrolled648ConditionsRisk ReductionArmsPioglitazone Plus dapaglifliozin, Placebo
NCT04791826 nacompletednot on this mapstarted 2021, after this paper: background citation

Evaluation of an EMR-Based Clinical Decision Support Tool for the Implementation of Guideline-Directed Therapies for Prevention of Heart Failure Among High-Risk Patients With Type 2 Diabetes

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2021 to 2024Enrolled1,524ConditionsHeart Failure, Diabetes Mellitus, Type 2ArmsOn-screen electronic alert
3 · Its place in the literature

Who cites it

743 citing papers in PubMed, 6 syntheses or guidelines pooled it, 2,090 citations in OpenAlex.

  1. Dapagliflozin in Heart Failure: A Comprehensive Meta-analysis on Functional Capacity, Symptoms, and Safety Outcomes.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024
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683 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

W B Kannel
M Hjortland
W P Castelli
National Heart Lung and Blood Institute · USLung Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes ComplicationsAge FactorsArteriosclerosisBlood PressureBody WeightCholesterolCoronary DiseaseDiabetes MellitusDiabetic AngiopathiesDisease SusceptibilityFemaleFollow-Up StudiesHeart DiseasesHeart FailureHumansInsulinCholesterolInsulin

Identifiers

PMID4835750
OpenAlexW2135378280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.