ArticleThe American journal of cardiology1974
Physiologic basis for assessing critical coronary stenosis. Instantaneous flow response and regional distribution during coronary hyperemia as measures of coronary flow reserve.
Article in The American journal of cardiology, 1974. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 300 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of the Antidiabetic Drug DAPAgliflozin on the Coronary Macrovascular and MICROvascular Function in Type 2 Diabetic Patients
Anatomical Assessment Versus Pull Back REsting Full-cycle rAtio (RFR) Measurement for Evaluation of Focal and Diffuse Coronary Disease
Who cites it
300 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Coronary Microvascular Dysfunction in Patients with Congenital Heart Disease.Current cardiology reviews · 2023Pooled it
- Advances in Myocardial Perfusion MR Imaging: Physiological Implications, the Importance of Quantitative Analysis, and Impact on Patient Care in Coronary Artery Disease.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022Pooled it
- Coronary collaterals and risk for restenosis after percutaneous coronary interventions: a meta-analysis.BMC medicine · 2012Pooled it
- Determining the Physiological Threshold for Angina (ORBITA-FIRE): A Double-Blind, Randomized, Placebo-Controlled Study.Circulation · 2026Trial
- Optimal medical care and coronary flow capacity-guided myocardial revascularization vs usual care for chronic coronary artery disease: the CENTURY trial.European heart journal · 2025Trial
- Coronary microvascular dysfunction in patients with stable coronary artery disease: The CE-MARC 2 coronary physiology sub-study.International journal of cardiology · 2018Trial
- Coronary flow velocity reserve by echocardiography: feasibility, reproducibility and agreement with PET in overweight and obese patients with stable and revascularized coronary artery disease.Cardiovascular ultrasound · 2016Trial
- Transmural myocardial perfusion gradients in relation to coronary artery stenoses severity assessed by cardiac multidetector computed tomography.The international journal of cardiovascular imaging · 2015Trial
- Carotid artery stenosis near a bifurcation investigated by fluid dynamic analyses.The neuroradiology journal · 2013Trial
- Coronary flow reserve varies depending upon the location within the artery it is assessed and the TIMI myocardial perfusion grade: a PROTECT TIMI-30 analysis.Journal of thrombosis and thrombolysis · 2011Trial
- Intracoronary physiological indices for coronary microvascular dysfunction: from concept to clinical application.Cardiovascular intervention and therapeutics · 2026Review
- Coronary plaque burden and composition in an ESC guideline-selected outpatient CCTA cohort: age- and sex-specific percentile distributions.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Clinical Correlation of the Folts Model of Ischemia in a Middle-Aged Woman With Poorly Controlled Type 2 Diabetes.Journal of medical cases · 2026Article
- Predictive ability of microvascular resistance reserve for periprocedural myocardial injury in patients with stable coronary artery disease undergoing percutaneous coronary intervention.Heart and vessels · 2026Article
- A Machine Learning Driven Approach to Quantifying Coronary Artery Tortuosity.JACC. Advances · 2026Article
- Absolute coronary blood flow measurement and the principle of microvascular resistance reserve.Cardiovascular intervention and therapeutics · 2026Review
- Coronary pathophysiology in idiopathic pulmonary arterial hypertension.JCI insight · 2026Article
- PAPP-A Protein Diagnostic and Prognostic Significance in Acute Coronary Syndromes Without Persistent ST-T-Segment Elevation.Journal of clinical medicine · 2026Article
- Coronary Physiology Across the Whole Spectrum of Ischemic Heart Disease.Journal of clinical medicine · 2026Review
- Angiography-derived index versus fractional flow reserve for intermediate coronary lesions: a meta-analysis review.REC, interventional cardiology · 2026Article
240 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
4808557What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.