ArticleGut1973
The effect of medium-chain triglyceride on 47 calcium absorption in patients with primary biliary cirrhosis.
Article in Gut, 1973. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 14 citations in OpenAlex.
- Trial
- The role of mitochondria-related key genes in primary biliary cholangitis was analyzed based on transcriptome sequencing data.Frontiers in immunology · 2025Article
- Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis.World journal of gastroenterology · 2015Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calcium absorption, as measured by whole-body retention of isotopic (47)calcium, was investigated in 10 controls and 10 patients with primary biliary cirrhosis before and after medium-chain triglyceride therapy. Absorption of calcium was impaired in eight patients with primary biliary cirrhosis, three of whom had normal serum bilirubin. Mean absorption was significantly less in patients with primary biliary cirrhosis than in controls. Impaired calcium absorption correlated well with increased faecal fat excretion and less well with the intensity of jaundice. Osteoporosis was diagnosed radiologically in seven patients with primary biliary cirrhosis, and calcium absorption was restored to normal in seven out of eight patients after medium-chain triglyceride therapy. Decrease of steatorrhoea, weight gain, and relief of bone pain have been noted in most patients with primary biliary cirrhosis after therapy. It is concluded that bone disease occurs early in primary biliary cirrhosis, and early medium-chain triglyceride therapy in these patients is suggested.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.