The coronary drug project. Findings leading to further modifications of its protocol with respect to dextrothyroxine. The coronary drug project research group.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it.

1. Niacin for primary and secondary prevention of cardiovascular events.The Cochrane database of systematic reviews · 2017 · on this map
   Pooled it
2. Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73).BMJ (Clinical research ed.) · 2016
   Pooled it
3. Improved adherence adjustment in the Coronary Drug Project.Trials · 2018
   Trial
4. Coronary drug project: experience with niacin. Coronary Drug Project Research Group.European journal of clinical pharmacology · 1991 · on this map
   Trial
5. Effect of neomycin sulphate alone and in combination with D-thyroxine on serum lipoproteins in hypercholesterolaemic subjects.European journal of clinical pharmacology · 1982
   Trial
6. Adverse effects of hypolipidaemic drugs.Medical toxicology
   Trial
7. Thyroid disorders and cardiovascular manifestations: an update.Endocrine · 2022
   Review
8. Hypovitaminosis D and Low T3 Syndrome: A Link for Therapeutic Challenges in Patients with Acute Myocardial Infarction.Journal of clinical medicine · 2021
   Article
9. The Alcohol-High-Density Lipoprotein Athero-Protective Axis.Biomolecules · 2020
   Review
10. Novel uses of thyroid hormones in cardiovascular conditions.Endocrine · 2019
    Review
11. Nonalcoholic Fatty Liver Disease and Hypercholesterolemia: Roles of Thyroid Hormones, Metabolites, and Agonists.Thyroid : official journal of the American Thyroid Association · 2019
    Review
12. Conditional power as an aid in making interim decisions in observational studies.European journal of epidemiology · 2018
    Article
13. Direct effects of thyroid hormones on hepatic lipid metabolism.Nature reviews. Endocrinology · 2018
    Review
14. Potential Role of Thyroid Receptor β Agonists in the Treatment of Hyperlipidemia.Drugs · 2017
    Review
15. Thyroid function and ischemic heart disease: a Mendelian randomization study.Scientific reports · 2017
    Article
16. Thyroid hormones and cardiovascular disease.Nature reviews. Cardiology · 2017
    Review
17. Role of the Thyroid System in the Dynamic Complex Network of Cardioprotection.European cardiology · 2016
    Review
18. Adherence adjustment in the Coronary Drug Project: A call for better per-protocol effect estimates in randomized trials.Clinical trials (London, England) · 2016
    Article
19. Thyroid Hormone Mimetics: the Past, Current Status and Future Challenges.Current atherosclerosis reports · 2016
    Review
20. New Insights into the High-Density Lipoprotein Dilemma.Trends in endocrinology and metabolism: TEM · 2016
    Review

Corrections and comments

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Authors and funding

0 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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