The Coronary Drug Project. Initial findings leading to modifications of its research protocol.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it.

1. Niacin for primary and secondary prevention of cardiovascular events.The Cochrane database of systematic reviews · 2017 · on this map
   Pooled it
2. Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73).BMJ (Clinical research ed.) · 2016
   Pooled it
3. Secondary prevention of ischaemic cardiac events.BMJ clinical evidence · 2011
   Pooled it
4. Improved adherence adjustment in the Coronary Drug Project.Trials · 2018
   Trial
5. Risk factors associated with cardiovascular events during testosterone administration in older men with mobility limitation.The journals of gerontology. Series A, Biological sciences and medical sciences · 2013
   Trial
6. Coronary drug project: experience with niacin. Coronary Drug Project Research Group.European journal of clinical pharmacology · 1991 · on this map
   Trial
7. Estrogen Influences Human Microvascular Endothelial Function Via Sex-Specific Regulation of Sphingolipids.JACC. Basic to translational science · 2026
   Article
8. Feminizing Hormone Therapy in the Male Spontaneous Hypertensive Rat Impairs Accuracy of Estimated Renal Filtration.Journal of the Endocrine Society · 2025
   Article
9. Cross-Sex Hormone Therapy Is Associated With Loss of Circadian Rhythm in the Male Rat.Hypertension (Dallas, Tex. : 1979) · 2025
   Article
10. International society of sports nutrition position stand: nutritional concerns of the female athlete.Journal of the International Society of Sports Nutrition · 2023
    Review
11. Ethics Committees: Structure, Roles, and Issues.Journal of Korean medical science · 2023
    Review
12. Cardiovascular disease and feminizing gender-affirming hormone therapy: Implications for the provision of safe and lifesaving care.Current opinion in physiology · 2023
    Article
13. Sex hormones, adiposity, and metabolic traits in men and women: a Mendelian randomisation study.European journal of endocrinology · 2022
    Article
14. Medical transition for gender diverse patients.Current obstetrics and gynecology reports · 2020
    Article
15. Cardiovascular implications of gender-affirming hormone treatment in the transgender population.Maturitas · 2019
    Review
16. Conditional power as an aid in making interim decisions in observational studies.European journal of epidemiology · 2018
    Article
17. The effects of oestrogens and their receptors on cardiometabolic health.Nature reviews. Endocrinology · 2017
    Review
18. Gender, Estrogen, and Obliterative Lesions in the Lung.International journal of endocrinology · 2017
    Review
19. Adherence adjustment in the Coronary Drug Project: A call for better per-protocol effect estimates in randomized trials.Clinical trials (London, England) · 2016
    Article
20. All cholesterol-lowering interventions are expected to reduce stroke: Confirmatory data from IMPROVE-IT.Data in brief · 2016
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

0 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as