ReviewObesity surgery2026
Weight, Fat Mass, and Lean Mass Changes After Bariatric Surgery and GLP-1-Based Therapy: A Systematic Review and Meta-Analysis.
Review in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic and bariatric surgery (MBS) and GLP-1-based therapies both reduce weight, but their effects on body composition are not directly comparable across measurement methods. We systematically reviewed 31 studies; 30 studies comprising 5,616 participants were included in random-effects meta-analyses stratified by dual-energy X-ray absorptiometry or bioelectrical impedance analysis, with 12 months as the primary timepoint. In both modalities, MBS was associated with greater total weight and absolute fat-mass loss than GLP-1-based therapy. Greater absolute lean-mass loss accompanied the larger weight reduction, without establishing poorer proportional lean-mass preservation. Relative fat-mass change differed by modality, and heterogeneity was substantial. These indirect subgroup comparisons should not be interpreted as head-to-head treatment effects. Standardized comparative studies incorporating muscle strength and physical function are needed.
Identifiers
43024141What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.