Evidence map›Paper›PMID 43022956›Full record

ArticleACS omega2026

Ophiopogonin D' Targets PPM1B to Suppress B‑Cell Acute Lymphoblastic Leukemia via Disruption of Wnt/β-Catenin Signaling.

Teng Liu, Jiayu Liu, Bowen Liu, Runqing Gong, Xiaohui Tang, Zhi-Yuan Lu

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Teng LiuDepartment of Clinical Research, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China.
Jiayu LiuSchool of Pharmacy, Jining Medical University, Jining 272067, Shandong, China.
Bowen LiuDepartment of Clinical Research, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China.
Runqing GongDepartment of Clinical Research, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China.
Xiaohui TangDepartment of Clinical Research, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China.
Zhi-Yuan LuDepartment of Clinical Research, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China.ORCID https://orcid.org/0000-0001-8969-6195

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B-cell acute lymphoblastic leukemia (B-ALL) carries a dismal prognosis in adults due to the scarcity of effective targeted therapies, underscoring an urgent need for novel agents. Ophiopogonin D' (OPD'), a steroidal saponin structurally distinct from Ophiopogonin D (differing in aglycone and glycosylation), is isolated from

Identifiers

PMID43022956
PMCPMC13756644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.