ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2026
Placental-Neural Cross Talk: Biological Mechanisms Shaping Brain Architecture.
Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
Funding
Abstract
Impact of placental function on normal and pathological brain processes and supported behavior is an integrative research area dubbed "neuroplacentology." Placental functional genetics, structure, and vascular function have been discovered to have links to multiple clinical outcomes: autism, schizophrenia, and developmental cognitive impairment in offspring and postpartum depression and cognition in mothers. There are significant data showing that long-term impacts of preterm birth, diseases of pregnancy (preeclampsia), and maternal stress and depression may all be mediated by placental mechanisms, providing clinical and translational insights. Here, we will provide an up-to-date introduction to this emerging field. Mechanistic links between variations in placental structure and function and features of human and animal brain development and function will be discussed, clarifying basic biological connections and highlighting new targets to prevent clinical impairments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.