Evidence map›Paper›PMID 43013142›Full record

ArticleWorld journal of microbiology & biotechnology2026

Phycoerythrin attenuates Pseudomonas aeruginosa - induced pathogenesis, oxidative stress and intestinal dysfunction in Caenorhabditis elegans.

Bhargavi Sonavane, Mahek Karangiya, Aastha Sevak, Niraj Kumar Singh, Seema Amin, Datta Madamwar

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Article in World journal of microbiology & biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bhargavi SonavaneDepartment of Biological Sciences, Faculty of Science, P. D. Patel Institute of Applied Sciences, Charotar University of Science & Technology, CHARUSAT Campus, Changa, Anand District, Gujarat, 388421, India.ORCID http://orcid.org/0000-0002-5589-9039
Mahek KarangiyaDepartment of Biological Sciences, Faculty of Science, P. D. Patel Institute of Applied Sciences, Charotar University of Science & Technology, CHARUSAT Campus, Changa, Anand District, Gujarat, 388421, India.
Aastha SevakDepartment of Biological Sciences, Faculty of Science, P. D. Patel Institute of Applied Sciences, Charotar University of Science & Technology, CHARUSAT Campus, Changa, Anand District, Gujarat, 388421, India.
Niraj Kumar SinghSchool of Forensic Science, National Forensic Sciences University, (An Institution of National Importance, MHA, GoI), Nagpur, Maharashtra, 440022, India.ORCID http://orcid.org/0000-0002-2365-2314
Seema AminDepartment of Biological Sciences, Faculty of Science, P. D. Patel Institute of Applied Sciences, Charotar University of Science & Technology, CHARUSAT Campus, Changa, Anand District, Gujarat, 388421, India.
Datta MadamwarDepartment of Biological Sciences, Faculty of Science, P. D. Patel Institute of Applied Sciences, Charotar University of Science & Technology, CHARUSAT Campus, Changa, Anand District, Gujarat, 388421, India. datta_madamwar@yahoo.com.ORCID http://orcid.org/0000-0003-3301-1120

Funding

Gujarat Council on Science and Technology, Department of Science and Technology, Government of Gujarat, Gandhinagar, Gujarat, India GUJCOST/STI/2021-22/3878
6 · The paper itself

Abstract

Cyanobacterial phycobiliprotein, is widely known for its antioxidant, cytoprotective and antimicrobial agent. Using the Caenorhabditis elegans model (C. elegans), we evaluated the lifespan and intestinal integrity along with the oxidative and stress signalling pathways. In the present study, the protective role of phycoerythrin (PE) treatment was evaluated against Pseudomonas aeruginosa (PA), well known pathogen posing risk to both environment and organism. Crude PE extracted from Haplosiphon sp. was purified using ammonium sulphate precipitation and ion-exchange chromatography and was characterized using SDS-PAGE and UV-Visible Spectroscopy, yielding purified PE with an A553/A280 purity ratio of 5.5. Further, the antioxidant potential of PE was demonstrated using in-vitro DPPH (2,2-diphenyl-1-picrylhydrazyl) (IC

Indexed as

Caenorhabditis elegansIntestinesOxidative StressPhycoerythrinPseudomonas aeruginosaAnimalsAnti-Bacterial AgentsAntioxidantsPseudomonas InfectionsSignal TransductionAnti-Bacterial AgentsAntioxidantsPhycoerythrinAntioxidant activityCaenorhabditis elegansOxidative stressPhycoerythrinPseudomonas aeruginosa

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.