Evidence map›Paper›PMID 43013102›Full record

ArticleEnvironmental geochemistry and health2026

Drinking water hardness and nervous system mortality: a 15 year ecological study of calcium and magnesium content in the Slovak Republic.

Stanislav Rapant, Nina Beňová, Veronika Cvečková, Beata Stehlíková, Natalia Hunarova, Andrea Ižarik-Verešpejová, Martin Kolísek

Abstract read
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Article in Environmental geochemistry and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stanislav RapantFaculty of Natural Sciences, Comenius University Bratislava, Ilkovičova 6, 842 15, Bratislava, Slovak Republic.ORCID http://orcid.org/0000-0002-9921-7722
Nina BeňováFaculty of Natural Sciences, Comenius University Bratislava, Ilkovičova 6, 842 15, Bratislava, Slovak Republic.ORCID http://orcid.org/0009-0005-2247-3858
Veronika CvečkováDionýz Štúr State Geological Institute, Mlynská Dolina 1, Bratislava, 817 04, Slovak Republic.
Beata StehlíkováFaculty of Economics and Business, Institute of Economics, Pan-European University, Tomášiková 20, Bratislava, 821 02, Slovak Republic.
Natalia HunarovaInstitute of Medical Biochemistry, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic. hunarova2@uniba.sk.ORCID https://orcid.org/0009-0008-5371-0950
Andrea Ižarik-VerešpejováInstitute of Medical Biochemistry, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic.ORCID http://orcid.org/0009-0008-6474-7492
Martin KolísekJessenius Faculty of Medicine in Martin, Martin Biomedical Center, Comenius University Bratislava, Malá Hora 4D, Martin, 036 01, Slovak Republic.ORCID http://orcid.org/0000-0001-8962-4511

Funding

LifeScan LIFE17 ENV/SK/000036
6 · The paper itself

Abstract

The chemical composition of the natural physical environment significantly impacts human health, yet the specific influence of drinking water minerals on nervous system disorders remains largely unexamined. This study investigated the relationship between drinking water hardness, specifically calcium and magnesium concentrations, and nervous system disease mortality across populations in the Slovak Republic. Two size wise comparable groups of rural municipalities supplied exclusively by public water systems were monitored over a 15 year period (1994-2008), totaling 1.58 million person-years. The soft water cohort comprised 34 municipalities (Ca ≤ 25 mg L

Indexed as

CalciumDrinking WaterMagnesiumNervous System DiseasesHumansSlovakiaCalciumDrinking WaterMagnesiumCerebral palsyDrinking waterEpilepsyNervous systemWater hardness

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.