ArticleFrontiers in digital health2026
Autonomous digital lifestyle intervention for obesity: a comparative study of software-generated vs. provider-delivered body composition outcomes.
Article in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Background: Many lifestyle intervention apps for weight management rely on human coaching, which increases cost and variability, or use calorie-counting approaches that lack structured, individualized guidance. Fully autonomous digital platforms that deliver personalized nutrition and exercise plans with body composition tracking remain limited. Objective: To compare an autonomous, protein-focused digital lifestyle intervention (RightBMI App) with provider-delivered lifestyle intervention for weight loss and body composition outcomes in metabolic and bariatric surgery (MBS) candidates. Materials and methods: This prospective quasi-experimental study enrolled 160 patients at a single center (April 2024-April 2025). Patients were sequentially allocated to the RightBMI App ( Results: In GEE models, the App group showed significantly greater %TBWL at weeks 12 (+2.64%, Conclusion: The autonomous RightBMI App demonstrated greater mid-study weight and fat loss compared with provider-delivered care after statistical adjustment, with comparable 24-week outcomes and effective muscle preservation. Time-to-event analysis showed no significant difference in time to achieve ≥10% TBWL. These findings support the potential of fully autonomous digital platforms as scalable alternatives to traditional provider-led interventions in MBS candidates. Limitations include the non-randomized design and use of consumer-grade bioimpedance scales.
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