ReviewReviews in cardiovascular medicine2026
Exploration of the Pathogenesis and Treatment of Heart Failure.
Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heart failure represents the terminal stage of various cardiac diseases; the global prevalence of heart failure has been steadily increasing and poses a significant public health burden. With ongoing advances in molecular biology, clinical epidemiology, and translational medicine, research on heart failure has progressed significantly. Thus, understanding of the pathogenesis of heart failure has expanded beyond traditional hemodynamic abnormalities to encompass multidimensional, interrelated mechanisms, including neurohumoral imbalance, myocardial remodeling (hypertrophy and fibrosis), energy metabolism disorders, epigenetic regulation, and gut microbiota dysbiosis. This review systematically summarizes recent key advances in elucidating heart failure pathogenesis and iterative updates to treatment strategies, drawing on fundamental and translational research in this field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.