Evidence map›Paper›PMID 42979440›Full record

ReviewActa pharmaceutica Sinica. B2026

Pharmacological agents for promoting diabetic wound healing.

Jiamin Shang, Zhaoyu Liu, Meidai Liang, Xiaomeng Ye, Zijie Yin, Zeyu Yang, Jiaqi Zhao, Hongjing Wu, Guanhua Du, Xiuying Yang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Acta pharmaceutica Sinica. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiamin ShangBeijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases, Institute of Materia Medica of Peking Union Medical College, Beijing 100050, China.
Zhaoyu LiuBeijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases, Institute of Materia Medica of Peking Union Medical College, Beijing 100050, China.
Meidai LiangDepartment of Pharmacy, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing 102218, China.
Xiaomeng YeBeijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases, Institute of Materia Medica of Peking Union Medical College, Beijing 100050, China.
Zijie YinBeijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases, Institute of Materia Medica of Peking Union Medical College, Beijing 100050, China.
Zeyu YangBeijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases, Institute of Materia Medica of Peking Union Medical College, Beijing 100050, China.
Jiaqi ZhaoBeijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases, Institute of Materia Medica of Peking Union Medical College, Beijing 100050, China.
Hongjing WuBeijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases, Institute of Materia Medica of Peking Union Medical College, Beijing 100050, China.
Guanhua DuBeijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases, Institute of Materia Medica of Peking Union Medical College, Beijing 100050, China.
Xiuying YangBeijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases, Institute of Materia Medica of Peking Union Medical College, Beijing 100050, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic wounds are highly susceptible to chronicity and infection due to impaired healing involving multiple pathophysiological factors. Despite extensive preclinical and clinical research, few approved drugs have been shown to effectively accelerate diabetic wound healing. This review highlights pharmacological interventions for diabetic wound healing, summarizes the current status of drug development, and discusses their potential mechanisms of action. These agents include inflammation-modulating agents, pro-proliferative agents, remodeling-regulating agents, hypoxia- and microcirculation-targeting agents, antioxidant agents, and multi-target agents, such as bioactive constituents from plants and traditional Chinese medicine (TCM) formulas. This review aims to guide future drug development strategies for diabetic wound healing.

Indexed as

Diabetic foot ulcerDrug deliveryDrug developmentInflammationMechanismOxidative stressPharmacological agentsWound healing

Identifiers

PMID42979440
PMCPMC13729541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.