Evidence map›Paper›PMID 42979039›Full record

ArticleAACE endocrinology and diabetes

Digital Cognitive Behavioral Therapy Reduces Intensification of Antihyperglycemic Therapy in Patients With Type 2 Diabetes.

Judith Hsia, Nicole L Guthrie, Mark A Berman, Kara Mosesso, Björn Hansell, Marc P Bonaca

Abstract read
In one paragraph

Article in AACE endocrinology and diabetes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Judith HsiaDepartment of Medicine, University of Colorado School of Medicine and CPC Clinical Research, Aurora, Colorado.
Nicole L GuthrieBetter Therapeutics, Inc., San Francisco, CA (acquired by Click Therapeutics, Inc, New York, NY).
Mark A BermanBetter Therapeutics, Inc., San Francisco, CA (acquired by Click Therapeutics, Inc, New York, NY).
Kara MosessoBetter Therapeutics, Inc., San Francisco, CA (acquired by Click Therapeutics, Inc, New York, NY).
Björn HansellBetter Therapeutics, Inc., San Francisco, CA (acquired by Click Therapeutics, Inc, New York, NY).
Marc P BonacaDepartment of Medicine, University of Colorado School of Medicine and CPC Clinical Research, Aurora, Colorado.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We evaluated the effect of cognitive behavioral therapy delivered via a novel digital therapeutic application (app) on antihyperglycemic medication use in adults with type 2 diabetes. Methods: Trial participants were randomized to receive access to BT-001 or a control app for 180 days. Antihyperglycemic medications were adjusted as needed, consistent with the standard of care, and all concomitant therapies were permitted. Change in antihyperglycemic medication from the baseline to the study exit was compared between treatment groups. Results: Among 668 randomized participants, the mean number of antihyperglycemic medications at the baseline was 2 ± 1 for both groups. The increase in number or dose of medications from the baseline to the study exit was greater in the control group compared with the BT-001 group ( Conclusions: BT-001, the first prescription digital therapeutic authorized for treatment of type 2 diabetes, significantly reduced intensification of antihyperglycemic therapy compared to the control app and reduced insulin usage.

Indexed as

antihyperglycemic therapyDigital cognitive behavioral therapytype 2 diabetes

Identifiers

PMID42979039
PMCPMC13728308

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.