ArticleAACE endocrinology and diabetes
Risk Factors for Sarcopenic Obesity in Adults: A Case-Control Study Using Bioelectrical Impedance Analysis.
Article in AACE endocrinology and diabetes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Sarcopenic obesity (SO) is the coexistence of excess adiposity and low muscle mass or function, with underrecognized prevalence and poorly defined risk factors in adults. Methods: This retrospective, observational, case-control study analyzed records from a tertiary-care center (2022-2024). Adults ≥30 years who underwent bioelectrical impedance analysis were included. Sarcopenia was defined by appendicular lean mass /height Results: A total of 56 patients were classified as SO and 407 as non-SO controls. The overall mean (SD) age was 52.3 (10.2) years and males were the predominant sex [252 (54.4%)]. Female sex, lower physical activity, and lower body mass index were significantly associated with SO in univariate analyses. In the multivariable model (Nagelkerke R Conclusions: SO was significantly associated with modifiable factors. Despite neutral effects in prior studies, in this study metformin use and regular exercise were protective, whereas proton pump inhibitor use, elevated triglycerides, and dyslipidemia were risk factors. These findings highlight the need for targeted prevention strategies beyond body mass index, especially in adult populations.
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