Observational studyJournal of diabetes2026
Body Mass Index, Cardiometabolic Treatment Patterns and Multifactorial Risk-Factor Control in Chinese Adults With Type 2 Diabetes: A Multicenter Cross-Sectional Study.
Observational study in Journal of diabetes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
9 authors.
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Abstract
backgroundTo examine medication use and simultaneous achievement of glycemic, blood pressure and lipid targets across body mass index (BMI) categories in Chinese adults with Type 2 diabetes.
methodsThis BMI-focused secondary cross-sectional analysis included 8590 adults with evaluable BMI recruited from 60 hospitals in the iCaReMe China Registry. The primary comparison was obesity versus normal weight for simultaneous achievement of HbA1c < 7.0%, blood pressure < 130/80 mmHg and LDL cholesterol < 2.6 mmol/L. Missing data were handled by multiple imputation (20 datasets; 20 iterations per chain), and associations were estimated with center-clustered generalized estimating equations (GEE).
resultsThe cohort comprised 99 (1.2%) adults with underweight, 2725 (31.7%) normal weight, 3663 (42.6%) overweight, and 2103 (24.5%) obesity. Among 6683 with all three observed components, 332 (5.0%) achieved the composite. Compared with normal weight, the pooled adjusted OR for obesity was 0.55 (95% CI 0.39-0.78); each 1-kg/m
conclusionsObesity was associated with lower odds of simultaneous target attainment, with component-specific associations for glycemia and blood pressure but not LDL-C. GLP-1 receptor agonists and SGLT2 inhibitors were used more often at higher BMI; these prescribing patterns do not establish treatment effectiveness.
trial registrationChiCTR2300073764.
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