Evidence map›Paper›PMID 42959881›Full record

ArticleACS omega2026

Cadmium Exposure Aggravates SREBP-1c-Mediated Hepatic Steatosis and Liver Injury in High-Fat Diet-Fed Mice.

Shuying Wu, Yaqian Li, Yuru Zong, Qibin Mai, Ruirui Qiu, Huidong Song, Hanqing Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuying WuThe Affiliated Guangzhou Twelfth People's Hospital, Guangzhou Medical University, Guangzhou 510515, China.
Yaqian LiThe Affiliated Guangzhou Twelfth People's Hospital, Guangzhou Medical University, Guangzhou 510515, China.
Yuru ZongBeijing Key Laboratory of Environment and Aging, Department of Nutrition and Food Hygiene, School of Public Health, Capital Medical University, Beijing 100069, China.
Qibin MaiThe Affiliated Guangzhou Twelfth People's Hospital, Guangzhou Medical University, Guangzhou 510515, China.
Ruirui QiuThe Affiliated Guangzhou Twelfth People's Hospital, Guangzhou Medical University, Guangzhou 510515, China.ORCID https://orcid.org/0009-0007-8603-3231
Huidong SongThe Affiliated Guangzhou Twelfth People's Hospital, Guangzhou Medical University, Guangzhou 510515, China.
Hanqing ChenBeijing Key Laboratory of Environment and Aging, Department of Nutrition and Food Hygiene, School of Public Health, Capital Medical University, Beijing 100069, China.ORCID https://orcid.org/0000-0001-5442-2071

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) is a persistent environmental heavy metal that bioaccumulates and is associated with diverse toxicities. Metabolic dysfunction-associated steatotic liver disease (MASLD) is highly prevalent, and steatotic metabolic stress may increase vulnerability to toxicological insults. In this study, we used a free fatty acid (FFA)-treated hepatocyte model and high-fat diet (HFD)-fed steatotic mice to characterize hepatic responses to a short-term CdCl

Identifiers

PMID42959881
PMCPMC13717757

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.