Evidence map›Paper›PMID 42958461›Full record

ArticleJournal of health, population, and nutrition2026

Association of medical visit frequency with cardiovascular events and mortality in patients with dyslipidaemia: a cohort study using a Japanese claims database.

Taku Matsunaga, Eiji Nakatani, Yasuto Sato, Hideaki Kaneda, Hiromitsu Ohno, Akira Sugawara

Abstract read
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Article in Journal of health, population, and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Taku MatsunagaGraduate School of Public Health, Shizuoka Graduate University of Public Health, 4-27-2 Kitaando, Aoi-ku, Shizuoka, 420-0881, Japan.
Eiji NakataniGraduate School of Public Health, Shizuoka Graduate University of Public Health, 4-27-2 Kitaando, Aoi-ku, Shizuoka, 420-0881, Japan. nakatani.eiji.int@gmail.com.ORCID https://orcid.org/0000-0002-4876-446X
Yasuto SatoGraduate School of Public Health, Shizuoka Graduate University of Public Health, 4-27-2 Kitaando, Aoi-ku, Shizuoka, 420-0881, Japan.
Hideaki KanedaOkinaka Memorial Institute for Medical Research, Tokyo, Japan.
Hiromitsu OhnoAllied Medical K.K, Tokyo, Japan.
Akira SugawaraGraduate School of Public Health, Shizuoka Graduate University of Public Health, 4-27-2 Kitaando, Aoi-ku, Shizuoka, 420-0881, Japan. asugawara@s-sph.ac.jp.

Funding

Shizuoka Prefecture Nothing
6 · The paper itself

Abstract

backgroundDyslipidaemia is a major risk factor for cardiovascular and cerebrovascular diseases; however, the optimal frequency of medical visits remains unclear.

objectiveTo examine whether medical visit frequency is associated with the incidence of cardiac events, cerebrovascular events, and mortality among patients initiating lipid-lowering therapy.

methodsWe conducted a retrospective cohort study using data from the Shizuoka Kokuho Database between April 1, 2012, and September 30, 2021. Patients initiating lipid-lowering therapy were classified into high-frequency (≥ 22 visits in 2 years) and low-frequency (8-12 visits in 2 years) groups. After 1:3 propensity score matching and exclusion of patients with events within 2 years, 1,435 patients in the low-frequency group and 4,412 in the high-frequency group were analysed.

resultsOver a mean follow-up of 5.3 years, composite outcomes occurred in 5.6% of both groups (hazard ratio [HR] 1.08; 95% confidence interval [CI] 0.84-1.38; p = 0.571). No significant differences were observed for cardiac events (HR 1.13; 95% CI 0.83-1.54), cerebrovascular events (HR 1.13; 95% CI 0.67-1.90), or mortality (HR 0.94; 95% CI 0.60-1.48).

conclusionLess frequent visits were not associated with increased risks of cardiovascular events or mortality. Extending visit intervals may therefore be a reasonable option for selected stable patients receiving lipid-lowering therapy for primary prevention.

Indexed as

Cardiovascular DiseasesDyslipidemiasOffice VisitsAgedCerebrovascular DisordersDatabases, FactualEast Asian PeopleFemaleHumansHypolipidemic AgentsIncidenceJapanMaleMiddle AgedRetrospective StudiesRisk FactorsHypolipidemic AgentsCardiovascular diseasesDyslipidaemiasMortalityPatient follow-upPrimary health careStroke

Identifiers

PMID42958461
PMCPMC13721620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.