Evidence map›Paper›PMID 42955273›Full record

ArticleGlobal health action2026

Mapping the neurobiological landscape linking obesity with selected psychiatric conditions: global trends and emerging hotspots.

Chang Liu, Chaonan Dong, Xiang Zhou, Qi Shu, Fan Zhang, Ronglin Cai, Qing Yu

Abstract readEvidence Synthesis
In one paragraph

Article in Global health action, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chang LiuThe First Clinical Medical College, Anhui University of Chinese Medicine, Hefei, China.ORCID 0009-0006-4999-3551
Chaonan DongCollege of Acupuncture-Moxibustion and Tuina, Anhui University of Chinese Medicine, Hefei, China.ORCID 0009-0006-3078-9665
Xiang ZhouCollege of Traditional Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China.ORCID 0009-0007-6084-9558
Qi ShuCollege of Traditional Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China.ORCID 0000-0002-7322-0798
Fan ZhangSchool of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China.ORCID 0000-0003-1720-6235
Ronglin CaiCollege of Acupuncture-Moxibustion and Tuina, Anhui University of Chinese Medicine, Hefei, China.ORCID 0000-0001-5666-6280
Qing YuCollege of Acupuncture-Moxibustion and Tuina, Anhui University of Chinese Medicine, Hefei, China.ORCID 0000-0002-1600-2647

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity frequently co-occurs with a range of psychiatric conditions, creating an important global public health challenge. However, neurobiological research on these associations remains fragmented across disciplines, and a systematic bibliometric synthesis is lacking.

objectiveTo map the knowledge structure, identify research hotspots, and characterize temporal trends in neurobiological research linking obesity with selected psychiatric conditions.

methodsRelevant literature (2010-2025) was retrieved from the Web of Science Core Collection. Following screening, 476 studies were included. Bibliometric and visualization analyses were conducted using VOSviewer, CiteSpace, and Scimago Graphica. A supplementary Scopus analysis assessed publication overlap and concordance in selected bibliometric indicators.

resultsPublications surged after 2021, with the last 5 years accounting for 54.2% of the total. The United States and China had the highest publication counts. Among the 10 most productive countries, France had the highest mean annualized citations per publication. Core hotspots include neuroinflammation, the gut-brain axis, hypothalamic-pituitary-adrenal (HPA) axis dysfunction, and high-fat diet.

conclusionNeuroinflammation, the gut-brain axis, and HPA-axis-related processes emerged as recurring themes. These findings highlight the need for further investigation of metabolic, immune, and neural processes in geographically diverse populations, particularly in developing regions.

Indexed as

Mental DisordersObesityBibliometricsBrain-Gut AxisGlobal HealthHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemBibliometricsgut-brain axishypothalamic-pituitary-adrenal (HPA) axisneuroinflammationnutritional psychiatry

Identifiers

PMID42955273
PMCPMC13721829

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.