Evidence map›Paper›PMID 42948549›Full record

ArticleO&G open2026

The Association Between Glucose Intolerance and Longitudinal Fetal Growth in Nulliparas.

Alexandra Mahdasian-Miller, Armando Peña, David Haas, Maisa Feghali, Lynn Yee, Jessica Wilder, Nathan Blue, Celeste Durnwald, Jonathan Steller, Christina M Scifres

Registry-linked trialAbstract read
In one paragraph

Article in O&G open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01322529 (Preterm Birth in Nulliparous Women), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01322529 completednot on this map

Preterm Birth in Nulliparous Women: An Understudied Population at Great Risk

TypeobservationalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran2010 to 2015Enrolled10,038ConditionsPregnancy, Pregnancy Complications
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexandra Mahdasian-MillerDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.
Armando PeñaDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.
David HaasDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.
Maisa FeghaliDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.
Lynn YeeDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.
Jessica WilderDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.
Nathan BlueDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.
Celeste DurnwaldDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.
Jonathan StellerDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.
Christina M ScifresDepartment of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Health & Wellness Design, School of Public Health, Indiana University, Bloomington, Indiana; Department of Obstetrics & Gynecology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Obstetrics & Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Obstetrics & Gynecology, Case Western Reserve University, Cleveland, Ohio; Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics & Gynecology, University of California Irvine School of Medicine, Irvine, California; and Department of Obstetrics & Gynecology, Indiana University School of Medicine, and Regenstrief Institute, Indianapolis, Indiana.

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063036 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI PARKER, CORETTE BREEDEN · 2010 to 2015
$19.5M
Institute for Clinical and Translational ScienceUL1TR000153 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M · 2012 to 2015
$12.1M
Prevention of Preterm Birth in high Risk Nulliparous PatientsU10HD063047 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WAPNER, RONALD · 2010 to 2014
$1.9M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063053 · NICHD · UNIVERSITY OF UTAH · PI SILVER, ROBERT M. · 2010 to 2014
$1.7M
Preterm Birth in Nulliparous Women: An Understudied Population at Great Risk U10HD063020 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GROBMAN, WILLIAM ADAM · 2010 to 2014
$1.6M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063046 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI WING, DEBORAH A · 2010 to 2014
$1.6M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063041 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SIMHAN, HYAGRIV N · 2010 to 2014
$1.5M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063048 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI PARRY, SAMUEL I. · 2010 to 2014
$1.5M
Dissecting the Genetic Etiology of Preterm Birth in Nulliparous WomenU10HD063037 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI HAAS, DAVID M. · 2010 to 2014
$1.2M
Adverse Outcomes in Nulliparous Pregnancies: The Ohio CollaborativeU10HD063072 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI MERCER, BRIAN M. · 2010 to 2014
$1.2M
NCATS NIH HHS UL1 TR000153NCATS NIH HHS UL1 TR001108NICHD NIH HHS U10 HD063020NICHD NIH HHS U10 HD063036NICHD NIH HHS U10 HD063037NICHD NIH HHS U10 HD063041NICHD NIH HHS U10 HD063046NICHD NIH HHS U10 HD063047NICHD NIH HHS U10 HD063048NICHD NIH HHS U10 HD063053NICHD NIH HHS U10 HD063072
6 · The paper itself

Abstract

objectiveTo evaluate fetal growth patterns and birth weight among individuals with normoglycemia, mild glucose intolerance, and gestational diabetes mellitus (GDM) from midgestation until delivery.

methodsThis is a secondary analysis of the NuMoM2b (Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be) prospective cohort of nulliparous individuals with singleton gestations. Maternal glucose tolerance was categorized as normal, mild glucose intolerance (one abnormal Carpenter-Coustan value), or GDM. Blinded ultrasounds at 16-22 weeks and 22-29 weeks provided fetal biometry

resultsAmong 7,010 included participants, 175 (2.5%) had mild glucose intolerance, and 290 (4.1%) had GDM. Fetal biometry was similar across groups at 16-22 weeks. By 22-29 weeks, GDM was associated with accelerated fetal growth

conclusionFetal overgrowth associated with glucose intolerance emerges around the standard 24- to 28-week GDM screening window. Individuals with GDM had an LGA risk similar to those with normal glucose tolerance, consistent with the increased surveillance and clinical management associated with a GDM diagnosis attenuating the trajectory of excess fetal growth. Whether treatment of mild glucose intolerance can reduce LGA risk remains to be determined. CLINICAL

trial registrationClinicalTrials.gov, NCT01322529.

Identifiers

PMID42948549
PMCPMC13713061

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.