Evidence map›Paper›PMID 42947927›Full record

ArticleJournal of diabetes and metabolic disorders2026

Association of conventional and non-conventional lipid profile with cognitive impairment among type 2 diabetic patients.

Behnaz Esmaeili, Elahe Hesari, Kazem Khalaji, Farshad Sharifi, Nekoo Panahi, Afshin Ostovar, Iraj Nabipour, Mahnaz Sanjari, Shahnaz Esmaeili

Abstract read
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Article in Journal of diabetes and metabolic disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Behnaz EsmaeiliDepartment of Basic Medical Sciences, Khoy University of Medical Sciences, Khoy, Iran.
Elahe HesariOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Kazem KhalajiObesity and Eating Habits Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Farshad SharifiElderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Nekoo PanahiMetabolic Disorders Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Afshin OstovarOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Iraj NabipourThe Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.
Mahnaz Sanjari *Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Shahnaz Esmaeili *Department of Basic Sciences/Medical Surgical Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To explore the connection between atherogenic index of plasma, non-HDL-C, as well as conventional lipid profiles in relation to cognition dysfunction among the diabetic participants aged over 60 years. Methods: The data of this cross-sectional research study came from the Bushehr Elderly Health (BEH) Program (Phase II) carried on the participants aged 60 and above. The functional status of the participants was assessed using the Functional Assessment Staging tool (FAST) and Category Fluency Test (CFT). After the measurement of lipid parameters, we used multiple logistic regression to analyze their relationship with cognitive impairment (CI) among the participants. Results: There were 836 participants in this cross-sectional study. Of them, 339 had cognitive decline. The average age of the subjects was 68.6 ± 5.7 years. There was no relationship between lipid parameters and cognition dysfunction with the exception of HDL-C. A higher amount of HDL-C had a protective role. While older age (OR = 1.05, 95% CI = 1.01-1.08, Conclusion: Among conventional lipid profiles, only the HDL-C levels were related to cognitive dysfunction and no relationship was observed between cognitive impairment and non-conventional lipids.

Indexed as

CholesterolCognitive impairmentDiabetesDyslipidemiaLipid parameters

Identifiers

PMID42947927
PMCPMC13710469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.