Evidence map›Paper›PMID 42946937›Full record

Observational studyInternational ophthalmology2026

Changes in pupillographic and ocular surface parameters following upper eyelid blepharoplasty.

Elmas Yüksel Şükün, Sibel Sipahioğlu

Abstract readObservational Study
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Observational study in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Elmas Yüksel ŞükünDepartment of Ophthalmology, Alanya Training and Research Hospital, Oba, Fidanlık Street, 07400, Alanya/Antalya, Turkey. dr.elmas.yuksel@gmail.com.ORCID https://orcid.org/0000-0003-3320-3739
Sibel SipahioğluDepartment of Ophthalmology, Alanya Training and Research Hospital, Oba, Fidanlık Street, 07400, Alanya/Antalya, Turkey.ORCID https://orcid.org/0000-0001-6506-6885

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate changes in pupillary responses, meibomian gland morphology, and tear film stability following upper eyelid blepharoplasty and to characterize the postoperative patterns of these parameters at the third postoperative month.

methodsThis retrospective longitudinal observational study included 90 eyes of 45 patients (mean age, 57.6 ± 9.18 years) who underwent orbicularis-preserving upper eyelid blepharoplasty. Preoperative and third-month postoperative assessments comprised pupillography (scotopic, mesopic, and photopic pupil diameters; 10-s redilation velocity), non-contact infrared meibography, and noninvasive tear film breakup time (NI-FBUT and NI-AvgBUT). Preoperative and postoperative outcomes were analyzed using linear mixed-effects models to account for within-patient inter-eye correlation.

resultsPhotopic and mesopic pupil diameters showed significant postoperative reductions (p = 0.011 and p = 0.002, respectively), accompanied by a decrease in redilation velocity (p = 0.018), while scotopic pupil diameter remained unchanged. Meibomian gland loss area showed a mild, nonsignificant increase, while NI-FBUT and NI-AvgBUT showed nonsignificant postoperative increases.

conclusionsUpper eyelid blepharoplasty was associated with small reductions in mesopic and photopic pupil diameters and redilation velocity at the third postoperative month. No statistically significant changes were detected in the evaluated tear-film or meibography parameters. The physiological mechanisms underlying the observed pupillometric changes cannot be determined from the present study.

Indexed as

BlepharoplastyEyelidsMeibomian GlandsPupilTearsAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative PeriodRetrospective StudiesMeibographyOcular surfacePupillary responsePupillographyTear film stabilityUpper eyelid blepharoplasty

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.