Evidence map›Paper›PMID 42942919›Full record

ReviewNutrients2026

When Genetics Meets the Mediterranean Diet Across Metabolic Diseases.

Francesca Gorini, Mariangela Palazzo, Morena Gabriele, Andrea Borghini

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Francesca GoriniInstitute of Clinical Physiology, National Research Council, 56124 Pisa, Italy.ORCID 0000-0002-4619-6227
Mariangela PalazzoInstitute of Clinical Physiology, National Research Council, 56124 Pisa, Italy.
Morena GabrieleInstitute of Agricultural Biology and Biotechnology, National Research Council, 56124 Pisa, Italy.ORCID 0000-0002-9456-6755
Andrea BorghiniInstitute of Clinical Physiology, National Research Council, 56124 Pisa, Italy.ORCID 0000-0003-1061-8309

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic diseases and related cardiometabolic conditions, including type 2 diabetes (T2D), obesity, metabolic syndrome (MetS), and metabolic dysfunction-associated steatotic liver disease (MASLD), arise from complex interactions between genetic predisposition and environmental factors. Among dietary patterns, the Mediterranean diet (MedDiet) has consistently been associated with improved metabolic health and a reduced risk of cardiometabolic diseases. However, substantial interindividual variability in metabolic responses to dietary exposures suggests that genetic susceptibility may contribute to differences in response to the MedDiet. Over the past two decades, nutrigenetic research has investigated whether adherence to the MedDiet can modify the effects of genetic variants associated with metabolic risk. Initial studies focused primarily on candidate genes involved in glucose metabolism, adiposity regulation, circadian rhythms, and hepatic lipid metabolism, including variants in genes such as

Indexed as

Diet, MediterraneanMetabolic DiseasesDiabetes Mellitus, Type 2Gene-Environment InteractionGenetic Predisposition to DiseaseGenetic Risk ScoreHumansMetabolic SyndromeNutrigenomicsObesitygene–diet interactiongenetic risk scoregenetic susceptibilityMASLDMediterranean dietmetabolic syndromenutrigeneticsobesityprecision nutritiontype 2 diabetes

Identifiers

PMID42942919
PMCPMC13708031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.