ArticleLife (Basel, Switzerland)2026
Coronary and Peripheral Venous Inflammatory Biomarkers in Acute Myocardial Infarction: Associations with Myocardial Injury, Cardiac Function, and Clinical Outcomes.
Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
(1) Background: Interleukin-6 (IL-6) links innate immune activation to myocardial injury and adverse outcomes after acute myocardial infarction (AMI), yet the relationship between local intracoronary and systemic peripheral IL-6, and their prognostic value, remains unclear. (2) Methods: This prospective single-center study aimed to compare intracoronary and peripheral venous IL-6 and other inflammatory biomarkers in AMI, included 83 consecutive STEMI (ST-elevation myocardial infarction) or NSTEMI (non ST-elevation myocardial infarction) patients undergoing coronary angiography. Paired intracoronary and peripheral venous samples were obtained before revascularization and analyzed for IL-6, CRP, and ferritin, and correlated with LVEF (left ventricle ejection fraction), NT-proBNP, and a 30-day composite endpoint (death or heart failure hospitalization). (3) Results: Peripheral IL-6 exceeded intracoronary levels in 86.7% of patients (
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