Evidence map›Paper›PMID 42942133›Full record

ArticleInternational journal of molecular sciences2026

Aluminum Chloride-Induced Planarian Model with Cognitive Impairments Through Neuronal Damage, Neurotransmitter Imbalance, Apoptosis, and Oxidative Stress.

Qingxian Wang, Shixue Wang, Zhenbiao Xu, Linxia Song, Kexin Yang, Chunmei Zhang, Xiaorui Cheng

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qingxian WangInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Shixue WangInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Zhenbiao XuSchool of Life and Medicine, Shandong University of Technology, Zibo 255000, China.
Linxia SongSchool of Life and Medicine, Shandong University of Technology, Zibo 255000, China.
Kexin YangSchool of Life and Medicine, Shandong University of Technology, Zibo 255000, China.
Chunmei ZhangSchool of Life and Medicine, Shandong University of Technology, Zibo 255000, China.ORCID 0009-0008-7446-4664
Xiaorui ChengInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.

Funding

Central Guidance for Local Science and Technology Development Funds YDZX2023137National Natural Science Foundation of China 82374062; 82675239Science and Technology Projects of Xizang Autonomous Region XZ202601ZY0167
6 · The paper itself

Abstract

The prevalence of Alzheimer's disease has significantly increased, which will place a heavy burden on families and society. Cognitive impairment is a typical feature of Alzheimer's disease. Rodent models play a key role in AD research, but their considerable expense and slow development pose challenges to the pace of therapeutic discovery. Here, we established a new model of cognitive dysfunction in planarians using AlCl

Indexed as

Aluminum ChlorideApoptosisCognitive DysfunctionNeuronsNeurotransmitter AgentsOxidative StressPlanariansAlzheimer DiseaseAnimalsDisease Models, AnimalAluminum ChlorideNeurotransmitter AgentsAluminum chlorideAlzheimer’s diseasecognitive impairmenthigh-throughput screeningplanarian

Identifiers

PMID42942133
PMCPMC13704994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.