ArticleInternational journal of molecular sciences2026
Restoration of PPD-Induced Injury in iHDPCs via the OS-Mitochondrial Apoptosis Pathway: Screening and Validation of Natural Compounds.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
This study aimed to investigate the protective effects of curcumin (Cur), resveratrol (Res), and astragaloside IV (AS-IV) against p-phenylenediamine (PPD)-induced injury in human immortalized dermal papilla cells (iHDPCs), with a focus on phenotypic endpoints that are suggestive of the oxidative stress-mitochondrial apoptosis pathway. Putative core targets were predicted via network pharmacology and molecular docking, and cellular responses were evaluated using CCK-8, DCFH-DA, JC-1, and Annexin V/PI assays in both PPD- and H
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