ArticleAntioxidants (Basel, Switzerland)2026
Routine Nutritional, Inflammatory, and Redox-Related Biomarker Abnormality Burden Is Associated with Lower 12-Week Physical Performance After Cholecystectomy in Rehabilitation Outpatients.
Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Simple tools for characterizing functional vulnerability after cholecystectomy are lacking, particularly among patients referred for outpatient rehabilitation. We examined whether a cumulative count of routine nutritional, inflammatory, and redox-related biomarker abnormalities at the first physical medicine and rehabilitation (PM&R) visit was associated with 12-week physical performance. This single-center retrospective cohort included 184 adults assessed 14-180 days after cholecystectomy. The exposure counted abnormalities in zinc, 25-hydroxyvitamin D, homocysteine, albumin, and neutrophil-to-lymphocyte ratio. The primary outcome was the 12-week Short Physical Performance Battery (SPPB) total score. After multivariable adjustment, each additional abnormality was associated with a 0.49-point lower 12-week SPPB score (β = -0.49, 95% confidence interval = -0.80 to -0.18;
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