Evidence map›Paper›PMID 42939876›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Dietary Sodium Butyrate Alleviates Thiram-Induced Tibial Dyschondroplasia in Broilers by Improving Redox Homeostasis and Upregulating the Nrf2/HO-1 Pathway.

Jiawei Wang, Yongbo Hao, Shaoyang Han, Feifei Luo, Ziyi Zheng, Shuo Sun, Xi Sun, Yongkang Diao, Jiahao Zhao, Suqiao Chu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiawei WangCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Yongbo HaoCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Shaoyang HanCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Feifei LuoBureau of Agriculture and Rural Affairs of Jinzhou City, Jinzhou 052200, China.
Ziyi ZhengCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Shuo SunCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Xi SunCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Yongkang DiaoCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Jiahao ZhaoCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Suqiao ChuShijiazhuang Animal Husbandry Technology Extension Station, Shijiazhuang 050000, China.
Lijun HouBureau of Agriculture and Rural Affairs of Langfang City, Langfang 065000, China.
Boyang ShiHebei Provincial Station of Veterinary Drug and Feed, Shijiazhuang 050035, China.
Hui ChenCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Chong LiCollege of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China.

Funding

Natural Science Foundation of Hebei C2025204221Shijiazhuang "Unveiling the List and Leadership" Scientific Project for County-Level Specific Industries 247790642A
6 · The paper itself

Abstract

Oxidative stress-induced impairment of chondrocyte differentiation and bone homeostasis is pivotal in tibial dyschondroplasia (TD). Sodium butyrate has been shown to modulate gut microbiota, improve redox homeostasis, and support skeletal metabolism; however, whether it exerts protection against TD specifically through oxidative stress modulation remains unclear. A total of 210 one-day-old male Arbor Acres broilers were randomly allocated to three treatment groups, with seven replicate pens per group and 10 birds per pen. The birds were housed in a windowless, climate-controlled indoor poultry house with floor pens and rice-husk bedding. In a thiram-induced broiler TD model, dietary sodium butyrate (500 mg/kg) reshaped the gut microbiota by increasing beneficial genera (

Indexed as

bone metabolismgut microbiotaoxidative stresssodium butyratetibial dyschondroplasia

Identifiers

PMID42939876
PMCPMC13701647

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.