ReviewBiomolecules2026
Disulfidptosis, Hydrogen Sulfide, and Acute Kidney Injury: Emerging Mechanisms and Therapeutic Intersections.
Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Acute kidney injury (AKI), a sudden and rapid loss of renal function that is often reversible, encompasses metabolic dysfunction, oxidative stress, inflammation, cytoskeletal collapse, and finally, renal cell death. Besides various types of cell death, like apoptosis, pyroptosis, necroptosis, and ferroptosis, disulfidptosis could be associated with AKI. Disulfidptosis is a novel form of regulated cell death driven by aberrant disulfide stress, which is triggered in glucose-starved cells exhibiting high expression of SLC7A11 (Solute Carrier Family 7 Member 11), which is a cystine/glutamate antiporter. Additionally, disulfidptosis is characterized by a significant disruption in the NADPH/NADP
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