Evidence map›Paper›PMID 42934739›Full record

ArticleCardiovascular diabetology2026

Epicardial adipose tissue volume and nephropathy in people living with type 2 diabetes: the Kidn-EAT study.

Anaïs Andrieu, Sopio Tatulashvili, Siwar Hammami, Mohamed Lamine Mariko, Imen Rezgani, Lucie Allard, Meriem Sal, Ines Barka, Mohamed Zerguine, Sébastien Homs and 5 more

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Article in Cardiovascular diabetology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Anaïs AndrieuDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Sopio TatulashviliDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Siwar HammamiClinical Research Unit, AP-HP, Avicenne Hospital, Bobigny, France.
Mohamed Lamine MarikoDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Imen RezganiDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Lucie AllardDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Meriem SalDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Ines BarkaDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Mohamed ZerguineDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Sébastien HomsDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Pierre-Yves BrilletDepartment of Radiology, AP-HP, Avicenne Hospital, Bobigny, France.
Emmanuelle FabreBiochemistry Department, Avicenne and Jean Verdier Hospitals, AP-HP, Sorbonne Paris Nord University, Bobigny, France.
Coralie Bloch-QueyratClinical Research Unit, AP-HP, Avicenne Hospital, Bobigny, France.
Hélène BihanDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France.
Emmanuel CossonDepartment of Endocrinology-Diabetology-Nutrition, Avicenne Hospital, AP-HP, CRNH-IdF, CSO Ile de France Nord, Sorbonne Paris Nord University, Sorbonne Paris Cité, 125 rue de Stalingrad, Bobigny, France. emmanuel.cosson@aphp.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEpicardial adipose tissue (EAT), a visceral adipose tissue located between the pericardium and the myocardium, has been linked to cardiac issues. The present study aimed to evaluate the association between EAT volume and the presence of nephropathy and its components, i.e. albuminuria/creatininuria ratio (ACR) and estimated glomerular filtration rate (eGFR) classes, in patients living with type 2 diabetes (PwT2D). MATERIALS AND

methodsThe present study is a cross-sectional analysis of a retrospective cohort of 700 PwT2D who had a computed tomography scan to measure both their coronary artery calcium score and EAT volume (proprietary prototype, GE HealthCare), and available data for both eGFR and ACR.

resultsA total of 700 PwT2D (332 women) were included, of whom 295 patients had nephropathy (42.1%), including 87 (12.4%) with eGFR < 60 ml/min/1.73m

conclusionEAT volume was associated with nephropathy and especially with increased ACR in PwT2D. This association may be partly explained by metabolic and inflammatory mechanisms, potentially driven by EAT and/or other associated ectopic fat depots in PwT2D.

Indexed as

AdiposityDiabetes Mellitus, Type 2Diabetic NephropathiesEpicardial Adipose TissueGlomerular Filtration RateKidneyAgedAlbuminuriaBiomarkersCreatinineCross-Sectional StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesBiomarkersCreatinineAlbuminuria/creatininuria ratioEpicardial adipose tissueEstimated glomerular filtration rateNephropathyType 2 diabetesVisceral adipose tissue

Identifiers

PMID42934739
PMCPMC13711880

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.