Evidence map›Paper›PMID 42929962›Full record

ReviewGels (Basel, Switzerland)2026

Injectable Conductive Hydrogels as Multifunctional Bioactive Soft Interfaces for Skeletal Muscle Regeneration.

Xinping Wang, Jingyu Li, Ying Liao, Xiaomin Sun, Zuquan Hu, Lijing Teng

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinping WangEngineering Research Center for Bio-Perception Materials of Guizhou Province, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Gui'an New District, Guiyang 561113, China.
Jingyu LiEngineering Research Center for Bio-Perception Materials of Guizhou Province, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Gui'an New District, Guiyang 561113, China.
Ying LiaoEngineering Research Center for Bio-Perception Materials of Guizhou Province, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Gui'an New District, Guiyang 561113, China.
Xiaomin SunEngineering Research Center for Bio-Perception Materials of Guizhou Province, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Gui'an New District, Guiyang 561113, China.ORCID 0000-0001-6027-4722
Zuquan HuEngineering Research Center for Bio-Perception Materials of Guizhou Province, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Gui'an New District, Guiyang 561113, China.ORCID 0000-0003-4978-4363
Lijing TengEngineering Research Center for Bio-Perception Materials of Guizhou Province, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Gui'an New District, Guiyang 561113, China.

Funding

Excellent Young Talents Plan of Guizhou Medical University 2021-101Guizhou Provincial Basic Research Program (Natural Science) MS[2026]553
6 · The paper itself

Abstract

The skeletal muscle is an essential organ in exercise and energy metabolism and it significantly contributes to maintaining body posture, facilitating movement, and supporting overall health. The skeletal muscle has an intrinsic capacity for self-repair and functional restoration following minor injury. However, this reparative ability is limited, and in cases of volumetric muscle loss (VML) caused by traumatic injury or tumor resection, substantial muscle loss and functional impairments may occur. Injectable conductive hydrogels (ICHs) have received increasing attention in the repair and regeneration of VML due to their controlled conductivity and minimally invasive application. In ICHs, conductive mediums are introduced into a hydrogel to improve the electrical integration between hydrogel and host tissue, promoting skeletal muscle repair. Furthermore, shear-thinning ICHs that undergo in situ gelation can reduce the injury size and inflammation, thus approaching the clinical transformation target of conductive biomaterials. Notably, ICHs can also serve as carriers of bioactive molecules or cells to improve the cellular microenvironment in the injured region and induce skeletal muscle regeneration. This review focuses on exploring different conductive mediums integrated into ICHs, including their formation principles, key performance metrics, immunoregulatory activity, and potential applications in skeletal muscle regeneration. Additionally, this review emphasizes the future development and optimization of ICHs to enhance skeletal muscle repair and regeneration.

Indexed as

injectable conductive hydrogelsregenerative microenvironmentskeletal muscle regenerationsoft bioelectronics interfaces

Identifiers

PMID42929962
PMCPMC13704124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.