Evidence map›Paper›PMID 42920400›Full record

ArticleScandinavian journal of medicine & science in sports2026

Endurance Training Improves Insulin Sensitivity, Metabolic Flexibility, and Mitochondrial Function in Type 2 Diabetes.

Maria Hansen, Sophie Møller, Ida Blom, Kristine K Lange, Andreas K Ziegler, Johanne E Farlov, Jacob Borch, Sofie A Hesselager, Jonathan K Hansen, Anna Liebmann and 5 more

Abstract read
In one paragraph

Article in Scandinavian journal of medicine & science in sports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Maria HansenDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-3197-9998
Sophie MøllerThe August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-3714-2227
Ida BlomDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-1602-3031
Kristine K LangeDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0009-0002-8400-9055
Andreas K ZieglerDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-7024-8536
Johanne E FarlovDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jacob BorchDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0009-0008-1854-6876
Sofie A HesselagerDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0009-0008-4054-1430
Jonathan K HansenDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0009-0007-7974-8132
Anna LiebmannDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Mette H DalDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Thorbjörn ÅkerströmDiabetes Pharmacology, Novo Nordisk A/S, Måløv, Denmark.ORCID https://orcid.org/0000-0002-7330-1723
Jørn W HelgeDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-9724-5423
Ylva HellstenThe August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-2435-9558
Flemming DelaDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-9970-9535

Funding

Novo Nordisk
6 · The paper itself

Abstract

To determine how endurance training influences insulin sensitivity, metabolic flexibility, and mitochondrial function in individuals with and without type 2 diabetes (T2D). Insulin sensitivity (2-step hyperinsulinaemic-isoglycaemic clamp), metabolic flexibility, and mitochondrial respiratory capacity and H

Indexed as

Diabetes Mellitus, Type 2Endurance TrainingInsulin ResistanceMitochondriaAdultBlood GlucoseCase-Control StudiesFemaleGlucose Clamp TechniqueHumansHydrogen PeroxideMaleMiddle AgedBlood GlucoseHydrogen Peroxidehyperinsulinaemic clampmetabolic flexibilitymitochondrial respiratory capacitynon‐randomized studypeak fat oxidationreactive oxygen species

Identifiers

PMID42920400
PMCPMC13695046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.