Evidence map›Paper›PMID 42919998›Full record

ArticleArchives of virology2026

Isolation and genomic characterization of a Teetrevirus phage infecting Klebsiella quasipneumoniae with a putative SAMase gene.

Kewei Chen, Jiaxiang Li, Liang Zhou, Ruiji Ge, Kaiyang Zheng, Chenghao Xu, Yue Su, Shujuan Sun, Yantao Liang, Jinyan Xing and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kewei Chen *MOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China.ORCID http://orcid.org/0009-0000-6394-1041
Jiaxiang Li *MOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China.ORCID http://orcid.org/0009-0000-6360-2920
Liang Zhou *MOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China.
Ruiji Ge *MOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China.
Kaiyang ZhengMOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China.
Chenghao XuMOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China.
Yue SuMOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China.
Shujuan SunMOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China.
Yantao LiangMOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China. liangyantao@ouc.edu.cn.ORCID http://orcid.org/0000-0002-2477-8197
Jinyan XingThe Affiliated Hospital of Qingdao University, Qingdao, China. xingjy@qdu.edu.cn.
Min WangMOE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Marine Microbial Resource Center, Center for Ocean Carbon Neutrality, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, China. mingwang@ouc.edu.cn.ORCID http://orcid.org/0000-0002-2357-589X

Funding

the Fundamental Research Funds for the Central Universities 202172002the National Key Research and Development Program of China LSKJ202203201the National Natural Science Foundation of China 42120104006 and 42176111
6 · The paper itself

Abstract

Phages regulate bacterial populations in engineered ecosystems. However, wastewater associated phage lineages remain uncultured and poorly characterized. Here, we describe vB_KquP_T1, a bacteriophage infecting Klebsiella quasipneumoniae and exhibiting a lytic growth phenotype, isolated from urban wastewater. Genome-based phylogenomic analyses revealed that vB_KquP_T1 represents a distinct species-level lineage within the Teetrevirus of the Autotranscriptaviridae, closely related to uncultured viral genomes. Metagenomic recruitment from 234 global wastewater datasets reveals that vB_KquP_T1-like phages are widespread, with pronounced regional variation. Notably, the vB_KquP_T1 genome encodes a putative S-adenosyl-L-methionine hydrolase (SAMase)-like protein. Structural modeling and comparative analysis revealed a conserved structural architecture, while molecular docking predicted potential interactions with SAM-related ligands. These findings link an uncultured viral lineage to a cultivated representative and support the conservation of SAM metabolism-related auxiliary genes across tailed phages.

Indexed as

BacteriophagesGenome, ViralKlebsiellaViral ProteinsGenomicsModels, MolecularMolecular Docking SimulationPhylogenyWastewaterViral ProteinsWastewaterDistributionGenomic and phylogenetic analysisKlebsiellaPhageSAMase

Identifiers

PMID42919998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.