Evidence map›Paper›PMID 42919898›Full record

ReviewCommunications chemistry2026

Approaching life in a test tube with prebiotic chemistry.

Zbigniew L Pianowski

Abstract readReview
PubMed Publisher
In one paragraph

Review in Communications chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Zbigniew L PianowskiInstitute of Organic Chemistry, Karlsruhe Institute of Technology KIT, 76131, Karlsruhe, Germany. pianowski@kit.edu.ORCID http://orcid.org/0000-0002-2623-744X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of life on our planet occurred somewhere before 3.48 billion years ago, and was predated by a poorly defined period of appearance and accumulation of chemical intermediates commonly known as biomolecules - which includes amino acids, lipids, sugars and components of genetic polymers. While no fossils are known to science from that period of Earth's development, prebiotic chemistry tried to experimentally answer the question: which chemical processes, and under which conditions, could provide our planet with biomolecules in sufficient quantity and structural diversity to enable spontaneous life formation. Here, we present a chronological overview of the hypotheses that have driven the development of prebiotic chemistry, and of seminal experiments which were intended to prove or disprove these hypotheses.

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.