Evidence map›Paper›PMID 42919364›Full record

ArticleBMC oral health2026

An in vitro comparative study of the effects of soy milk and coconut milk on the microhardness of primary molar enamel after an acidic challenge.

Alireza Hasanalizadeh, Hajar Attarzadeh Jouzdani, Parvin Mirzakoucheki Boroujeni, Yasmina Aalizadeh

Abstract readComparative Study
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Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Alireza HasanalizadehDepartment of Pediatric Dentistry, School of Dentistry, Islamic Azad University (Isfahan) Branch, Isfahan, Iran.
Hajar Attarzadeh JouzdaniDepartment of Pediatric Dentistry, School of Dentistry, Islamic Azad University (Isfahan) Branch, Isfahan, Iran. h.attarzadeh@iau.ac.ir.
Parvin Mirzakoucheki BoroujeniDepartment of Operative Dentistry, School of Dentistry, Islamic Azad University (Isfahan) Branch, Isfahan, Iran.
Yasmina AalizadehDepartment of Pediatric Dentistry, School of Dentistry, Islamic Azad University (Isfahan) Branch, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis in vitro study aimed to compare the effects of soy milk and coconut milk on primary molar enamel microhardness after an acidic challenge. MATERIALS AND

methodsMicrohardness of 30 primary molar enamel blocks was measured using a Vickers tester. For the acidic challenge, they were immersed in citric acid with a pH of 3 for 25 h, and then their microhardness was measured again. The specimens were then randomly assigned to 3 groups (n = 10) for immersion in either soy milk, coconut milk, or artificial saliva (control) 3 times a day, each time for 5 min, for 7 days. Subsequently, they underwent microhardness test again. Data were analyzed by ANOVA, independent t-test, and LSD test (alpha = 0.05).

resultsThe enamel microhardness significantly increased after immersion in coconut milk compared with the value after acidic challenge within the same group (P = 0.035). However, the difference in microhardness was not significant between the coconut milk and artificial saliva groups after the intervention (P = 0.178). No significant microhardness change occurred after soy milk immersion (P = 0.121), and no difference was found between soy milk and artificial saliva groups (P = 0.289).

conclusionUnder in vitro conditions, coconut milk significantly increased enamel microhardness after an acidic challenge, while soy milk showed a non-significant increase. Neither plant milk demonstrated a significant effect on microhardness compared with artificial saliva.

Indexed as

CocosDental EnamelMolarSoy MilkTooth, DeciduousAnimalsCitric AcidHardnessHumansHydrogen-Ion ConcentrationIn Vitro TechniquesSaliva, ArtificialCitric AcidSaliva, ArtificialAcidic challengeArtificial salivaCoconut milkEnamel microhardnessPrimary molarSoy milk

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.