Evidence map›Paper›PMID 42919362›Full record

ArticleMalaria journal2026

Severe Plasmodium falciparum infection with multi-organ involvement in an asplenic patient: a case report.

Bolette Wittenberg, Gitte Nyvang Hartmeyer, David Fuglsang-Damgaard, Torsten Roed, Helle Hansson, Fredrikke Christie Knudtzen

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Malaria journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bolette WittenbergDepartment of Clinical Microbiology, Odense University Hospital, J. B. Winsloews Vej 4, 5000, Odense C, Denmark. bolette.wittenberg@rsyd.dk.
Gitte Nyvang HartmeyerDepartment of Clinical Microbiology, Odense University Hospital, J. B. Winsloews Vej 4, 5000, Odense C, Denmark.
David Fuglsang-DamgaardDepartment of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark.
Torsten RoedDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark.
Helle HanssonCenter for Translational Medicine and Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Fredrikke Christie KnudtzenClinical Center for Emerging and Vector Borne Infections, Department of Infectious Diseases, Odense University Hospital, Odense, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmodium falciparum is the leading cause of severe malaria. The spleen plays a central role in the clearance of the infection in conjunction with antimalarial treatment. Splenectomized patients lack sufficient clearance functions. We report a case of severe P. falciparum infection with multi-organ involvement acquired in Uganda in a splenectomized patient with a persistently high parasitemia level despite appropriate antimalarial treatment. The case emphasizes the challenges associated with severe malaria in asplenic patients.

Indexed as

Malaria, FalciparumPlasmodium falciparumSpleenSplenectomyAntimalarialsHumansMaleParasitemiaUgandaAntimalarialsantimalarial treatmentasplenic patienthigh parasitemia levelmulti-organ involvementPlasmodium falciparumpyknotic parasites

Identifiers

PMID42919362

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.