Evidence map›Paper›PMID 42919210›Full record

Observational studyBMC nephrology2026

Predictors of physical performance decline in patients receiving maintenance hemodialysis: a prospective observational study.

Elisângela Andrade Assis Madeira, Joyce Noelly Vitor Santos, Vitória Emanuelli Rodrigues Silva, Inara Caroline Marcelino Martins, Vanessa Gomes Brandão Rodrigues, Vanessa Kelly da Silva Lage, Ana Heloísa Santos Machado, Júlia Garcia de Castro Pereira, Frederico Lopes Alves, Maria Cecília Sales Mendes Prates and 9 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Elisângela Andrade Assis MadeiraPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0009-0000-3461-2417
Joyce Noelly Vitor SantosPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0000-0001-5244-9182
Vitória Emanuelli Rodrigues SilvaPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0000-0003-2012-4935
Inara Caroline Marcelino MartinsPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0009-0006-1398-1540
Vanessa Gomes Brandão RodriguesLaboratório de Inflamação e Metabolismo (LIM), Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, 5.000. Rodovia MGT 367 - Km 583 - Alto da Jacuba, Diamantina, 39100-000, Brazil.ORCID http://orcid.org/0000-0002-1221-0393
Vanessa Kelly da Silva LageLaboratório de Inflamação e Metabolismo (LIM), Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, 5.000. Rodovia MGT 367 - Km 583 - Alto da Jacuba, Diamantina, 39100-000, Brazil.ORCID http://orcid.org/0000-0002-0381-5622
Ana Heloísa Santos MachadoLaboratório de Inflamação e Metabolismo (LIM), Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, 5.000. Rodovia MGT 367 - Km 583 - Alto da Jacuba, Diamantina, 39100-000, Brazil.ORCID http://orcid.org/0009-0001-3601-1794
Júlia Garcia de Castro PereiraPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0009-0009-9434-3365
Frederico Lopes AlvesPrograma de Pós-Graduação em Ciências da Saúde (PPGCS), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0000-0001-8639-5020
Maria Cecília Sales Mendes PratesPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0000-0001-5202-773X
Emílio Henrique Barroso MacielPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0000-0001-8576-9297
Henrique Silveira CostaPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0000-0002-1426-7246
Marcus Alessandro de AlcantaraPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0000-0001-9233-0186
Camila Danielle Cunha NevesDepartamento de Atenção à Saúde do Trabalhador, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0003-0158-7918
Regina Márcia Faria de MouraHospital das Clínicas, EBSERH, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0002-1397-4838
Redha TaiarMATIM, Université de Reims Champagne, Ardenne, Reims, France.ORCID http://orcid.org/0000-0002-0227-3884
Ana Cristina Rodrigues LacerdaPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0000-0001-5366-3754
Pedro Henrique Scheidt FigueiredoPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.ORCID http://orcid.org/0000-0002-6748-3081
Vanessa Amaral MendonçaPrograma de Pós-Graduação em Reabilitação e Desempenho Funcional (PPGReab), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil. vanessa.mendonca@ufvjm.edu.br.ORCID http://orcid.org/0000-0002-1696-6091

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico , Brasil 409837/2024-5Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-00709-24Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-01522-23
6 · The paper itself

Abstract

objectiveTo identify predictors of physical performance decline in patients receiving maintenance hemodialysis.

methodsThis prospective observational study included patients receiving maintenance hemodialysis. Participants underwent assessment of physical performance using the Short Physical Performance Battery (SPPB), the 60-second sit-to-stand (60s-STS) test, handgrip strength, bone mineral density (BMD) by dual-energy X-ray absorptiometry (DEXA), and clinical and laboratory variables. Participants were classified according to changes in SPPB score between baseline and follow-up. The minimal detectable change (MDC) of the SPPB was used as the criterion for defining physical performance decline. Statistical analysis included Student's t-test, the Mann-Whitney test, and chi-square tests. Univariable logistic regression and multivariable penalized logistic regression with Firth correction were used to identify predictors of physical performance decline.

resultsOf the 103 participants, 18 (17.5%) experienced physical performance decline after a mean follow-up of 18.6 ± 10.1 months. Compared with those who maintained physical performance, participants with physical performance decline were older and had lower total and femoral bone mineral density and poorer performance on the 60s-STS test at baseline. In the multivariable penalized logistic regression analysis, lower femoral BMD (OR: 0.997; 95% CI: 0.991-0.999) and longer hemodialysis vintage (OR: 1.009; 95% CI: 1.001-1.039) were independently associated with physical performance decline.

conclusionThis prospective study showed that lower femoral bone mineral density and longer hemodialysis vintage were independently associated with physical performance decline in patients receiving maintenance hemodialysis. These findings underscore the potential value of longitudinal physical performance assessment and may help identify patients at greater risk of functional decline.

Indexed as

Kidney Failure, ChronicPhysical Functional PerformanceRenal DialysisAbsorptiometry, PhotonAgedBone DensityFemaleHand StrengthHumansMaleMiddle AgedProspective StudiesBone mineral densityChronic kidney diseaseHemodialysisPhysical performanceSDG 3: good health and well-being

Identifiers

PMID42919210

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.