Evidence map›Paper›PMID 42919182›Full record

ReviewBMC surgery2026

Complete resection of carina-level giant retrosternal goiters via a cervical approach with selective T-shaped extension of the cervical incision: a two-case report and literature review.

Lan Zhang, Yanzhao Wu, Peng Su, Mingbo Wang, Ping Shi

Abstract readCase ReportsReview
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In one paragraph

Review in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Lan ZhangDepartment of Otolaryngology-Head and Neck Surgery, The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital, No. 189 Tianshan Road, Shijiazhuang, Hebei, 050000, China.
Yanzhao WuDepartment of Otolaryngology-Head and Neck Surgery, The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital, No. 189 Tianshan Road, Shijiazhuang, Hebei, 050000, China.
Peng SuDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital, Shijiazhuang, Hebei, China.
Mingbo WangDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital, Shijiazhuang, Hebei, China.
Ping ShiDepartment of Otolaryngology-Head and Neck Surgery, The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital, No. 189 Tianshan Road, Shijiazhuang, Hebei, 050000, China. shirping@hebmu.edu.cn.

Funding

Department of Health of Hebei Province No. 20240378Hebei Provincial Department of Finance Government-funded Outstanding Medical Talents Project ZF2025197
6 · The paper itself

Abstract

backgroundGiant retrosternal goiter may extend to the carina or below while remaining biologically benign. The main operative challenge is not size alone but whether the mediastinal component can be safely mobilized under direct control of the airway, inferior vessels, recurrent laryngeal nerve (RLN), and parathyroid blood supply. We report two elderly patients with carina-level giant retrosternal goiters to illustrate individualized surgical route selection between a cervical incision alone and a cervical incision with selective T-shaped extended. CASE PRESENTATION: Two women aged 74 and 81 years underwent surgery for giant retrosternal goiter in 2025. Both underwent contrast-enhanced CT of the neck and chest, thyroid function testing, anesthetic assessment, multidisciplinary operative planning with thoracic surgical support, and preoperative blood typing and cross-matching with blood products available according to institutional protocol. In Case 1, the goiter had a substantial cervical component and extended to the carina. Complete resection was achieved through a cervical incision, but focal RLN transection occurred during difficult inferior-pole/thoracic-inlet dissection and was repaired immediately by end-to-end anastomosis. In Case 2, most of the goiter was retrosternal with minimal cervical bulk and extended approximately 1 cm below the carina. T-shaped extended cervical incision was added to improve exposure, allowing controlled complete resection with RLN preservation. Estimated blood loss was less than 150 mL in both patients. Final pathology confirmed nodular goiter. At 3 months, Case 1 had impaired right vocal-fold movement on laryngoscopy but no obvious hoarseness, subjective voice dissatisfaction, choking, or clinical aspiration. Case 2 had no significant laryngoscopic abnormality or voice/swallowing complaint. Both patients had no respiratory compromise, clinically significant calcium/PTH abnormality, symptomatic hypocalcemia, or clinical recurrence during short-term follow-up.

conclusionsThese two cases illustrate the need for individualized surgical route selection in carina-level giant retrosternal goiter. A cervical approach may be reasonable in selected patients when the lesion remains continuous with the cervical thyroid and the mediastinal component, inferior vessels, RLN, and parathyroid glands can be controlled safely under direct visualization. A T-shaped extended cervical incision is an effective adjunct when cervical exposure is inadequate, especially in elderly patients with a deep mediastinal component and minimal cervical bulk. Careful management of the recurrent laryngeal nerve, protection of the parathyroid blood supply, and intraoperative willingness to customize the exposure are essential for achieving complete resection with low morbidity.

Indexed as

Goiter, SubsternalThyroidectomyAgedAged, 80 and overFemaleHumansCervical incisionGiant retrosternal goiterLimited sternotomyRecurrent laryngeal nerveSubsternal goiter

Identifiers

PMID42919182

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.