Evidence map›Paper›PMID 42919176›Full record

ArticleBMC microbiology2026

Extracellular vesicles derived from Echinococcus granulosus hydatid cyst fluid may modulate liver fibrosis through 5-HT

Leyli Zanjirani Farahani, Soheila Rouhani, Fatemeh Mahdavi, Maryam Niyyati, Nasim Eslami, Majid Fasihi Harandi, Hamed Mirjalali

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Article in BMC microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Leyli Zanjirani FarahaniStudent Research Committee, Department of Medical Parasitology and Mycology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Soheila RouhaniDepartment of Medical Parasitology and Mycology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. srouhani11@yahoo.com.
Fatemeh MahdaviDepartment of Medical Parasitology and Mycology, school of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Maryam NiyyatiDepartment of Medical Parasitology and Mycology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nasim EslamiCells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
Majid Fasihi HarandiResearch Center for Hydatid Disease in Iran, Department of Parasitology, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Hamed MirjalaliFoodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran. hamedmirjalali@sbmu.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtracellular Vesicles (EVs) play an important role in cell communication, signal transduction, and the modulation of metabolic processes. The current study aimed to evaluate the effects of Echinococcus granulosus hydatid cyst fluid (HCF) and its EVs on serotonin receptors liver cell line.

resultsThe expression level of 5-HT

conclusionThe findings indicate that HCF and its EVs may alter serotonin receptors gene expression. These results suggest that HCF and its EVs may modulate the fibrosis pathways through decreasing the expression of 5-HT

Indexed as

Cyst FluidEchinococcosisEchinococcus granulosusExtracellular VesiclesLiver CirrhosisReceptor, Serotonin, 5-HT2BAlanine TransaminaseAnimalsAspartate AminotransferasesCell LineHumansAlanine TransaminaseAspartate AminotransferasesReceptor, Serotonin, 5-HT2BEchinococcus granulosusExtracellular VesiclesHydatid cyst fluidSerotonin receptor

Identifiers

PMID42919176

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.