Evidence map›Paper›PMID 42919175›Full record

ArticleBMC cancer2026

EIF3B is associated with m

Jiao Meng, Xinyi Jiang, Yaling Hu, Jinyue Tian, Zhenkun Yang, Zhening Pu, Ying Yin

Abstract read
PubMed Publisher
In one paragraph

Article in BMC cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiao Meng *Department of Laboratory Medicine, Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, Jiangsu, 214023, China.
Xinyi Jiang *Department of Laboratory Medicine, Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, Jiangsu, 214023, China.
Yaling HuDepartment of Laboratory Medicine, Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, Jiangsu, 214023, China.
Jinyue TianDepartment of Laboratory Medicine, Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, Jiangsu, 214023, China.
Zhenkun YangDepartment of Laboratory Medicine, Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, Jiangsu, 214023, China. yangzhkun@njmu.edu.cn.
Zhening PuDepartment of Laboratory Medicine, Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, Jiangsu, 214023, China. puzhening@njmu.edu.cn.
Ying YinDepartment of Laboratory Medicine, Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, Jiangsu, 214023, China. yinying83@njmu.edu.cn.

Funding

The Talents of Double Hundred Talent Plan BJ2023024
6 · The paper itself

Abstract

backgroundE2F transcription factors are key regulators of the cell cycle and play an important role in tumorigenesis. N6-methyladenosine (m

methodsWe applied weighted gene co-expression network analysis (WGCNA) to identify m

resultsFunctional validation revealed that EIF3B knockdown reduced E2F7 mRNA and protein expression, promoted E2F7 mRNA degradation, and decreased its m

conclusionsCollectively, these findings suggest that the EIF3B-E2F7 axis is associated with m

Indexed as

AdenosineBrain NeoplasmsEukaryotic Initiation Factor-3GlioblastomaNeoplastic Stem CellsCell Line, TumorGene Expression Regulation, NeoplasticHumansPrognosisRNA, MessengerRNA MethylationAdenosineEIF3B protein, humanEukaryotic Initiation Factor-3N-methyladenosineRNA, MessengerE2F7EIF3BGlioblastoma multiformem6A modificationStemness

Identifiers

PMID42919175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.