Evidence map›Paper›PMID 42919135›Full record

Observational studyBMC cardiovascular disorders2026

Multimodal non-invasive ultrasound for predicting severe coronary artery stenosis in right coronary dominant patients.

Kedan Hu, Qinghong Liu, Chunyan Li, Linru Zheng, Ling Luo, Ming Gao

Abstract readObservational Study
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Observational study in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Kedan HuDepartment of Ultrasound, Luzhou People's Hospital, Luzhou, 646000, China. 21454270@qq.com.
Qinghong LiuDepartment of Cardiology, Luzhou People's Hospital, Luzhou, 646000, China.
Chunyan LiDepartment of pediatrics, Luzhou People's Hospital, Luzhou, 646000, China.
Linru ZhengDepartment of Ultrasound, Luzhou People's Hospital, Luzhou, 646000, China.
Ling LuoDepartment of Ultrasound, Luzhou People's Hospital, Luzhou, 646000, China.
Ming GaoDepartment of Ultrasound, Luzhou People's Hospital, Luzhou, 646000, China.

Funding

Luzhou Science and Technology Plan Project 2021-JYJ-79
6 · The paper itself

Abstract

backgroundTo assess the predictive value of multimodal non-invasive ultrasound in detecting severe coronary artery stenosis (CAS) in patients with right coronary artery dominance.

methodsThis prospective observational study enrolled patients undergoing coronary angiography and non-invasive echocardiography at the Department of Cardiology, Luzhou People's Hospital, between December 2021 and August 2023. Severe CAS (SCAS) was defined as CAS ≥ 75% based on angiographic results. Patients were categorized into the SCAS group and the NSCAS group (non-severe CAS).

resultsA total of 121 patients were included, with 98 in the NSCAS group and 23 in the SCAS group. Compared to the NSCAS group, the SCAS group showed a lower left ventricular ejection fraction (LVEF) (49.3 ± 9.8% vs. 58.9 ± 5.2%, p = 0.028), a higher left ventricular end-systolic diameter(LVsd) (35.2 ± 7.7 mm vs. 29.8 ± 5.0 mm, p = 0.020), and a higher end-systolic volume༈ESV༉ (54.0 ± 23.0 ml vs. 35.7 ± 21.8 ml, p = 0.041). According to the receiver operating characteristic curve analysis, the optimal cutoff values for predicting SCAS are as follows: motion score, 1.5; ESV, 47.5 ml; LVsd, 30.5 mm; LVEF, 53.5%; mitral annular systolic velocity༈Smv༉, 8.5 cm/s; and global longitudinal peak strain༈GLPS༉, -16.5% (all p < 0.05). Multivariate logistic regression showed that LVEF was associated with SCAS (OR = 1.600, 95% CI:1.037-2.468, P = 0.034).

conclusionsOur findings suggest that LVEF may play a role in predicting SCAS, validating non-invasive ultrasound as an effective early diagnostic tool for patients with right coronary artery dominance.

trial registrationNot applicable.

Indexed as

Coronary StenosisCoronary VesselsAgedCoronary AngiographyFemaleGlobal Longitudinal StrainHumansMaleMiddle AgedMultimodal ImagingPredictive Value of TestsProspective StudiesReproducibility of ResultsSeverity of Illness IndexStroke VolumeVentricular Function, LeftCoronary artery diseaseCoronary artery stenosisGlobal longitudinal peak systolic strainNon-invasive ultrasoundReceiver operating characteristic curve

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.