Evidence map›Paper›PMID 42918912›Full record

ArticleInflammation2026

METTL14 Declines Th17/Treg Ratio Via the m6A Modification of DUSP23 to Alleviate Systemic Lupus Erythematosus.

Changjuan Xiao, Shaxi Ouyang, Peng Luo, Yuling Xiao, Yuting Gong, Xingwang Chen, Qinghua Zeng, Shuoshan Xie

Abstract read
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Article in Inflammation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Changjuan XiaoDepartment of Nephrology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, 61 Jiefangxi Road, Changsha, 410000, China.
Shaxi OuyangDepartment of Nephrology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, 61 Jiefangxi Road, Changsha, 410000, China.
Peng LuoDepartment of Nephrology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, 61 Jiefangxi Road, Changsha, 410000, China.
Yuling XiaoDepartment of Nephrology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, 61 Jiefangxi Road, Changsha, 410000, China.
Yuting GongDepartment of Nephrology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, 61 Jiefangxi Road, Changsha, 410000, China.
Xingwang ChenHunan Clinical Research Center for Chronic Kidney Disease, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, 61 Jiefangxi Road, Changsha, 410000, China.
Qinghua ZengDepartment of Nephrology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, 61 Jiefangxi Road, Changsha, 410000, China.
Shuoshan XieDepartment of Nephrology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, 61 Jiefangxi Road, Changsha, 410000, China. Xie_shuoshann@163.com.

Funding

Provincial Natural Science Foundation of Hunan 2024JJ9284
6 · The paper itself

Abstract

The imbalance between T helper (Th) 17 cells and regulatory T (Treg) cells is involved in the progression of systemic lupus erythematosus (SLE). Dual-specificity protein phosphatase 23 (DUSP23) expression is elevated in CD4

Indexed as

Dual-Specificity PhosphatasesLupus Erythematosus, SystemicMethyltransferasesMitogen-Activated Protein Kinase PhosphatasesTh17 CellsT-Lymphocytes, RegulatoryAdultAnimalsFemaleHumansMiceMice, Inbred MRL lprRNA MethylationDual-Specificity PhosphatasesMethyltransferasesMETTL14 protein, humanMitogen-Activated Protein Kinase PhosphatasesDUSP23Lupus erythematosusM6AMETTL14Th17/Treg differentiation

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.