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ArticleEuropean radiology2026

From dusk till dawn?-Night shift-induced fatigue, diagnostic performance, and AI assistance in chest radiography.

Robert Malte Siepmann, Mahta Khoobi, Marc Sebastian von der Stück, Felix Barajas Ordonez, Anca-Maria Theis, Malin Cubukcu, Maher Deeb, Manuel Post, Annika Rastkhiz, Eric Corban and 5 more

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Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Robert Malte SiepmannDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany. rsiepmann@ukaachen.de.ORCID http://orcid.org/0000-0002-4608-5180
Mahta KhoobiDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Marc Sebastian von der StückDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Felix Barajas OrdonezDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Anca-Maria TheisDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Malin CubukcuDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Maher DeebDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Manuel PostDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Annika RastkhizDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Eric CorbanDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Matthias ReenDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
David ToppDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Christiane KuhlDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Daniel TruhnDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
Sven NebelungDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.

Funding

Deutsche Forschungsgemeinschaft 515639690Deutsche Forschungsgemeinschaft 517243167Deutsche Forschungsgemeinschaft 701010997European Union Research and Innovation Programme ODELIA - GA 101057091European Union Research and Innovation Programme SAGMA - GA 101222556German Federal Ministry of Research, Technology and Space 01KD2420BGerman Federal Ministry of Research, Technology and Space 031L0312C
6 · The paper itself

Abstract

objectivesTo evaluate the impact of night shift-induced fatigue on radiology residents' diagnostic performance and to assess whether AI assistance offsets potential performance loss. MATERIALS AND

methodsIn this prospective intra-individual reader study, ten radiology residents (mean experience: 35 months; three women) interpreted three sets of 33 chest radiographs before and after a first-call on-site night shift. Sessions included two pre-shift readings (morning/afternoon, without AI) and two post-shift readings (morning, with/without AI). Eye tracking captured fixation duration and saccade count, and fatigue was defined as a ≥ 5% reduction in the slope of the saccadic main sequence between pre- and post-shift sessions. Diagnostic accuracy (Cohen's κ vs. expert majority vote), efficiency (mean reporting time per radiograph), eye-tracking metrics, and user surveys were analyzed with generalized linear mixed models and post-hoc Tukey-adjusted pairwise comparisons.

resultsSix of ten radiology residents were classified as fatigued, among whom diagnostic accuracy declined significantly post-shift (from κ = 0.71 ± 0.05 to κ = 0.61 ± 0.10; p < 0.001), with reduced fixation duration (p = 0.010) and saccade count (p = 0.015). Non-fatigued readers showed a smaller decline in accuracy (from κ = 0.72 ± 0.03 to κ = 0.65 ± 0.03; p = 0.037). Reporting times remained stable pre- and post-shift (p ≥ 0.463). AI assistance did not significantly improve diagnostic accuracy (Δκ = 0.03-0.04; p ≥ 0.525). Reporting times were numerically shorter with AI assistance in fatigued readers (Δ6.3 s; p = 0.122) and significantly shorter in non-fatigued readers (Δ9.9 s; p = 0.031). Surveys indicated mental exhaustion and reduced focus in fatigued readers.

conclusionNight-shift-induced fatigue impaired diagnostic accuracy without slowing reporting speed, raising patient safety concerns. The utilized AI model did not restore pre-shift performance. KEY POINTS: Question Night-shift-induced fatigue may reduce diagnostic accuracy of radiology residents in chest radiography, yet its objective quantification and the compensatory potential of AI assistance remain unclear. Findings Fatigue, based on eye-tracking measurements of oculomotor efficiency, reduced diagnostic accuracy after night shifts without slowing reporting speed; AI assistance did not significantly improve accuracy. Clinical relevance Night-shift-induced fatigue can lower diagnostic accuracy in chest radiography despite unchanged reporting speed, posing patient-safety risks. The AI model used in this study cannot fully compensate for fatigue-related performance decline.

Indexed as

Artificial intelligenceEye-tracking technologyRadiography, ThoracicShift work schedule

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.