Evidence map›Paper›PMID 42918868›Full record

ReviewNature reviews. Cancer2026

Cancer theranostics.

Alexandros Marios Sofias, Yvonne Derks, Michelle S Bradbury, Xiaoyuan Chen, Fabian Kiessling, Gooitzen M van Dam, Wolfgang A Weber, Twan Lammers

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandros Marios SofiasInstitute for Experimental Molecular Imaging (ExMI), RWTH Aachen University Hospital, Aachen, Germany.ORCID http://orcid.org/0000-0002-7475-2526
Yvonne DerksInstitute for Experimental Molecular Imaging (ExMI), RWTH Aachen University Hospital, Aachen, Germany.
Michelle S BradburyDepartment of Radiology, Molecular Imaging Innovations Institute, Weill Cornell Medical College, New York, NY, USA.ORCID http://orcid.org/0000-0003-3147-4391
Xiaoyuan ChenCenter for Nuclear Medicine and Molecular Imaging (CNMMI), Shandong Cancer Hospital and Institute, Jinan, People's Republic of China.ORCID http://orcid.org/0000-0002-9622-0870
Fabian KiesslingInstitute for Experimental Molecular Imaging (ExMI), RWTH Aachen University Hospital, Aachen, Germany.
Gooitzen M van DamTRACER Europe B.V, Groningen, The Netherlands.
Wolfgang A WeberDepartment of Nuclear Medicine, TUM University Hospital, Munich, Germany.ORCID http://orcid.org/0000-0002-7854-4345
Twan LammersInstitute for Experimental Molecular Imaging (ExMI), RWTH Aachen University Hospital, Aachen, Germany. tlammers@ukaachen.de.ORCID http://orcid.org/0000-0002-1090-6805

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Theranostics refers to the inseparable combination of disease diagnosis and therapy, with the former critically guiding the selection, application and outcome of the latter. In oncology, theranostics traditionally encompass radiolabelled peptides for in vivo molecular imaging of receptor expression by cancer cells, followed by radionuclide treatment using the same peptides labelled with β-emitting radioisotopes. Here we provide an overview of the basic principles and current clinical practice of theranostic probes and protocols, and we expand the terminology to include locally and systemically applied nanotheranostics and microtheranostics, as well as imaging-guided surgical interventions. Building on solid progress in target identification, probe design and hardware development, as well as on promising recent results achieved in clinical trials, we foresee a bright and broad future for multiscale theranostics, for the treatment of oncological pathologies and beyond.

Identifiers

PMID42918868

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.