ArticlePloS one2026
Incidence and predictors of mother-to-child transmission of HIV among HIV-exposed infants in public General hospitals of Tigray, Ethiopia, 2020: Retrospective cohort study.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) remains a major public health challenge, particularly in low-income countries. Previous studies conducted in Ethiopia were largely limited to single health facilities and did not adequately assess important predictors, including maternal viral load, paternal enrollment in antiretroviral therapy (ART), and breastfeeding duration. Therefore, this study aimed to determine the incidence and predictors of MTCT of HIV among HIV-exposed infants in public general hospitals of Tigray, Ethiopia.
methodsHospital-based retrospective cohort study on 485 randomly selected HIV exposed infants attending in public General Hospitals was conducted. All HIV exposed infants attending in public general hospitals of Tigray were the source of population. Data were entered into Epidata version 4.6.1 and exported to SPSS version 23 for analysis. Binary logistic regression model was used and variables at p-value < 0.25 in bivariate analysis were entered into a multivariable logistic regression analysis to examine the predictors of mother-to-child transmission of HIV. Level of significance was declared at p-value <0.05.
resultA total of 444(91.5%) records were included in the analysis. At the end of follow up, 17 (3.8%) (95% CI: 2.3%-5.8%) of the HIV exposed infants became HIV positive. Poor infant adherence (AOR: 5.6; 95% CI: 1.02-30.2), father not enrolled to ART (AOR: 4.4; 95% CI: 1.2-16.7), age of infant at enrolment >6 weeks (AOR: 4.4; 95% CI: 1.2-17.0), mothers enrolled to PMTCT during labor and delivery or after (AOR: 7.9; 95% CI: 1.4-44.7) and mothers on advanced WHO clinical stage at base line(AOR: 4.2; 95% CI: 1.02-17.89) were significantly associated with mother-to-child transmission of HIV.
conclusionIn this study MTCT of HIV is still high. Poor adherence of infant for PMTCT, HIV positive father not enrolled to ART, infant age > 6 weeks at enrollment, mothers enrolled to PMTCT during labor and delivery or after and mothers on advanced WHO clinical stage were predictors of mother to child transmission of HIV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.