ReviewEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026
Critical-sized bone defects: essential concepts for the higher orthopaedic examination.
Review in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo provide a practical review of the assessment and management of critical-sized bone defects (CSDs) for candidates preparing for higher orthopaedic examinations.
methodsThis narrative review considers definitions and classification, clinical assessment, acute management, reconstructive techniques and salvage options.
resultsA critical-sized bone defect (CSD) is unlikely to heal without intervention because of its size and location, although no numerical threshold defines criticality. Assessment should consider skeletal stability, infection, vascularity, soft tissues, host factors and likely function. After resuscitation, priorities include debridement, skeletal stabilisation and soft-tissue cover. Definitive bone loss should be assessed after debridement, which may require multiple operations. Reconstruction may be single-stage or staged. Options include bone grafting or acute shortening in selected cases, bone transport, the induced-membrane technique and vascularised bone transfer. Patient-specific implants show promise, but long-term evidence is limited. Planning should involve an orthoplastic team, with microbiology input if infection is suspected. Amputation should be considered if reconstruction is unlikely to yield a functional limb.
conclusionSuccessful management requires infection control, stable fixation and reliable soft-tissue cover. The reconstructive approach should reflect the defect and the patient's circumstances, balancing likely functional benefit against the burden of treatment.
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42911275What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.