Evidence map›Paper›PMID 42911275›Full record

ReviewEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026

Critical-sized bone defects: essential concepts for the higher orthopaedic examination.

Katie Hutchinson, Maria Vitenberg, Pramin Raut, Alex Trompeter

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katie HutchinsonSt George's University Hospitals NHS Foundation Trust, London, UK. katie.hutchinson16@nhs.net.ORCID https://orcid.org/0009-0009-0127-9529
Maria VitenbergSt George's University Hospitals NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0003-1819-9188
Pramin RautSt George's University Hospitals NHS Foundation Trust, London, UK.
Alex TrompeterSt George's University Hospitals NHS Foundation Trust, London, UK. a.trompeter@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide a practical review of the assessment and management of critical-sized bone defects (CSDs) for candidates preparing for higher orthopaedic examinations.

methodsThis narrative review considers definitions and classification, clinical assessment, acute management, reconstructive techniques and salvage options.

resultsA critical-sized bone defect (CSD) is unlikely to heal without intervention because of its size and location, although no numerical threshold defines criticality. Assessment should consider skeletal stability, infection, vascularity, soft tissues, host factors and likely function. After resuscitation, priorities include debridement, skeletal stabilisation and soft-tissue cover. Definitive bone loss should be assessed after debridement, which may require multiple operations. Reconstruction may be single-stage or staged. Options include bone grafting or acute shortening in selected cases, bone transport, the induced-membrane technique and vascularised bone transfer. Patient-specific implants show promise, but long-term evidence is limited. Planning should involve an orthoplastic team, with microbiology input if infection is suspected. Amputation should be considered if reconstruction is unlikely to yield a functional limb.

conclusionSuccessful management requires infection control, stable fixation and reliable soft-tissue cover. The reconstructive approach should reflect the defect and the patient's circumstances, balancing likely functional benefit against the burden of treatment.

Indexed as

Fractures, BoneOrthopedic ProceduresPlastic Surgery ProceduresBone TransplantationDebridementHumansLimb SalvageBone defectsBone lossDistraction osteogenesisFracture-related infectionNon-union

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.