Evidence map›Paper›PMID 42910548›Full record

ArticleThe Kaohsiung journal of medical sciences2026

Associations of the Baseline Level and Change in Triglyceride Glucose-Body Roundness Index With Cardiovascular Diseases: Two Large Prospective Cohorts in Europe and Asia.

Wen-Yang Han, Yi-Qun Li, Pin-Ni Yang, Yi-Ming Jia, Lu-Lu Sun, Rui-Rui Wang, Meng-Yao Shi, Xiao-Wei Zheng, Yong-Hong Zhang, Zheng-Bao Zhu

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In one paragraph

Article in The Kaohsiung journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wen-Yang HanDepartment of Public Health and Preventive Medicine, Public Health Research Center, Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.ORCID https://orcid.org/0009-0003-4915-9418
Yi-Qun LiDepartment of Public Health and Preventive Medicine, Public Health Research Center, Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Pin-Ni YangDepartment of Epidemiology, Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-Communicable Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, School of Public Health, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China.ORCID https://orcid.org/0000-0001-7327-3294
Yi-Ming JiaDepartment of Epidemiology, Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-Communicable Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, School of Public Health, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-3624-7879
Lu-Lu SunDepartment of Epidemiology, Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-Communicable Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, School of Public Health, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-9927-0654
Rui-Rui WangDepartment of Epidemiology, Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-Communicable Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, School of Public Health, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-2725-5228
Meng-Yao ShiDepartment of Epidemiology, Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-Communicable Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, School of Public Health, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-5883-0416
Xiao-Wei ZhengDepartment of Public Health and Preventive Medicine, Public Health Research Center, Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.ORCID https://orcid.org/0000-0002-4842-4852
Yong-Hong ZhangDepartment of Public Health and Preventive Medicine, Public Health Research Center, Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.ORCID https://orcid.org/0000-0001-6188-3490
Zheng-Bao ZhuDepartment of Epidemiology, Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-Communicable Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, School of Public Health, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China.ORCID https://orcid.org/0000-0001-5500-0014

Funding

Jiangsu Province Young Science and Technology Talent Support Program JSTJ-2025-474
6 · The paper itself

Abstract

The aim of this study was to investigate the association of baseline and changes of TyG-BRI with incident CVD based on the UK Biobank and China Health and Retirement Longitudinal Study (CHARLS). A total of 418,510 and 7923 individuals from the UK Biobank and CHARLS were included in Analysis 1 (baseline TyG-BRI with CVD risk). In Analysis 2 (change in TyG-BRI with CVD risk), a total of 11,682 and 4637 participants were included in Cox proportional hazard models. We found participants with the highest baseline TyG-BRI level were associated with increased risk of incident CVD in UK Biobank (HR = 1.45, 95% CI: 1.39-1.52) and CHARLS (HR = 1.35, 95% CI: 1.13-1.61). Multivariable-adjusted restricted cubic spline analyses presented positive linear associations between TyG-BRI and CVD risk. Compared to persistently low levels of TyG-BRI (Class 1), those with persistently high levels (Class 3: 1.23 (1.02-1.49) and 1.42 (1.11-1.55); Class 4: 1.48 (1.17-1.87) and 1.45 (1.16-2.28); Class 5: 2.58 (1.86-3.58) and 1.63 (1.16-2.28) for UK Biobank and CHARLS) in follow-up were associated with increased risks of incident CVD. In conclusion, a high baseline TyG-BRI level and different changes in TyG-BRI level are associated with increased risks of incident CVD.

Indexed as

CHARLSCVDtriglyceride‐glucose index with body round indexTyG‐BRI

Identifiers

PMID42910548
PMCPMC13688557

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.