Evidence map›Paper›PMID 42910463›Full record

ArticleNursing open2026

Nurse-Led Instant Message-Delivered Dyadic Intervention in Sodium Intake Reduction Knowledge, Attitude and Practice in Hypertensive Stroke Survivors: Randomised Controlled Trial Protocol.

Yongyang Yan, Man Ping Wang, Kui Kai Lau, Haobo Chen, Yong Yang, Zulian Yang, Fen Ye, Jung Jae Lee

Abstract readClinical Trial Protocol
In one paragraph

Article in Nursing open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yongyang YanSchool of Nursing, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.ORCID https://orcid.org/0000-0001-5879-8623
Man Ping WangSchool of Nursing, LKS Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China.ORCID https://orcid.org/0000-0003-4000-2388
Kui Kai LauDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China.ORCID https://orcid.org/0000-0002-8657-2418
Haobo ChenNeurology Department, Guangzhou First People's Hospital, Guangzhou, China.
Yong YangNeurology Department, Guangzhou First People's Hospital, Guangzhou, China.ORCID https://orcid.org/0009-0003-6324-6999
Zulian YangNeurology Department, Guangzhou First People's Hospital, Guangzhou, China.
Fen YeSchool of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0002-6734-1243
Jung Jae LeeSusan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0001-9704-2116

Funding

the Bau Tsu Zung Bau Kwan Yeu Hing Research and Clinical Fellowship
6 · The paper itself

Abstract

aimsTo evaluate the effectiveness of a nurse-led, instant message-delivered dyadic behavioural intervention on sodium intake reduction knowledge, attitude and practice (KAP) among stroke survivors with hypertension (HTN).

designA single-blind, two-arm parallel randomised controlled trial.

methodsA total of 110 stroke survivor-family caregiver dyads will be randomised. Dyads in the intervention group will receive 60 brief regular messages about sodium intake reduction education and practical skills, plus nurse-led real-time chat support via an instant messaging application (i.e., WeChat) for 2 months, while the control group will receive 10 brief regular messages about stroke education only. The primary outcome is stroke survivors' sodium intake reduction KAP immediately post-intervention (T1). Secondary outcomes include stroke survivors' KAP at 2-month follow-up (T2), blood pressure (BP), self-efficacy, quality of life and dyadic relationship (DR) at T1 and T2; family caregivers' sodium intake reduction KAP, self-efficacy, DR and caregiver burden at T1 and T2. Following intention-to-treat, the effects will be analysed using generalised estimating equations adjusting for covariates. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE: This study provides nurses with a replicable model for designing theory-driven, behaviour change technique-incorporated interventions targeting sodium intake reduction. Evidence on changes in KAP and BP among stroke survivors with HTN will inform nurse-led secondary stroke prevention strategies. IMPACT: By leveraging nurses and a widely accessible instant messaging platform, this study will demonstrate a scalable mobile health approach to address the leading dietary risk factor for stroke burden in China, potentially applicable to similar settings where sodium intake is amenable to behavioural interventions and contributing to the World Health Organization's global sodium reduction target. REPORTING

methodSPIRIT 2013 Statement. PATIENT OR PUBLIC CONTRIBUTION: Health professionals, stroke survivors and family caregivers were invited to evaluate the intervention development.

trial registrationChinese Clinical Trial Registry: ChiCTR2400086708.

Indexed as

Health Knowledge, Attitudes, PracticeHypertensionStrokeSurvivorsText MessagingCaregiversFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicSingle-Blind Method

Identifiers

PMID42910463
PMCPMC13688242

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.